CAJ | 학술논문

目的：探讨口底恶性副神经节瘤的临床表现、病理特征和治疗方法。方法报道口底恶性副神经节瘤1例,患者女,30岁,主诉“发现口底区肿胀1月余,影响言语及吞咽”入院,诊为口底肿物,全麻下行口底肿物切除术,完整切除肿瘤。结果术后病理确诊为口底恶性副神经节瘤,本例口底恶性副神经节瘤为无功能性,免疫组化结果为CK(-)、EMA(+)、Vim(+)、Des(-)、myoD1少量弱(+)、S-100(+)、GFAP弱(+)、syn(+)、CGA(+)、NSE(+)、NF(-)、CD34(-)、actin(弱+),PAS染色(-)。术后10 d拆线出院。结论口底恶性副神经节瘤缺乏特异的临床特征表现,易误诊,只有靠切除术后病理和免疫组化才能确诊。由于其非常罕见,相关治疗缺乏成熟的经验,故需要进一步研究。
목적：탐토구저악성부신경절류적림상표현、병리특정화치료방법。방법보도구저악성부신경절류1례,환자녀,30세,주소“발현구저구종창1월여,영향언어급탄인”입원,진위구저종물,전마하행구저종물절제술,완정절제종류。결과술후병리학진위구저악성부신경절류,본례구저악성부신경절류위무공능성,면역조화결과위CK(-)、EMA(+)、Vim(+)、Des(-)、myoD1소량약(+)、S-100(+)、GFAP약(+)、syn(+)、CGA(+)、NSE(+)、NF(-)、CD34(-)、actin(약+),PAS염색(-)。술후10 d탁선출원。결론구저악성부신경절류결핍특이적림상특정표현,역오진,지유고절제술후병리화면역조화재능학진。유우기비상한견,상관치료결핍성숙적경험,고수요진일보연구。
Objective Objective To investigate the clinical presentation, pathologic features and treatment of malignant paraganglioma of mouth floor. Methods We retrospectively studied a case of malignant paraganglioma of mouth floor. A 30-year-old woman with swell of the mouth floor for over 1 month was admitted to the hospital. After diagnosed as having tumor of the mouth floor, she underwent resection operation and the tumor was completely removed. Results Postoperative pathological examination confirmed the tumor to be malignant paraganglioma, which was non-functional, with the immunohistochemical results of CK(-), EMA(+), Vim(+), Des(-), myoD1(weak +), S-100(+), GFAP(weak +), syn(+), CGA(+), NSE(+), NF(-), CD34(-), actin(weak +), PAS(-). The patient had stitches out and discharged 10 days post-operation. Conclusion Lacking specific clinical characteristics,malignant paraganglioma of the mouth floor is easily misdiagnosed, and can be confirmed only by postoperative pathology and immunohistochemistry. For the treatment of this rare tumor, little experience has been accumulated, and further studies are needed.