CAJ | 학술논문

目的：了解北京市中关村医院（以下简称“我院”）呼吸科头孢菌素类抗菌药物的使用情况。方法：采用世界卫生组织推荐的用药频度（ DDDs）分析法，通过医院信息系统，统计2011—2013年我院呼吸科使用的头孢菌素类抗菌药物的药品名称、规格、数量等，计算出DDDs和销售金额并对其进行排序、分析。结果：近3年来，我院呼吸科使用的头孢菌素类抗菌药物的DDDs和销售金额均呈上升趋势；第3代头孢菌素使用的种类最多，且其DDDs和销售金额排序也居首位；第4代头孢菌素的DDDs和销售金额明显低于第3代和第2代头孢菌素。结论：我院呼吸科使用头孢菌素类抗菌药物较合理，但应严格控制第3代头孢菌素的用药指征，以提高疗效、延缓细菌耐药性的产生。
목적：료해북경시중관촌의원（이하간칭“아원”）호흡과두포균소류항균약물적사용정황。방법：채용세계위생조직추천적용약빈도（ DDDs）분석법，통과의원신식계통，통계2011—2013년아원호흡과사용적두포균소류항균약물적약품명칭、규격、수량등，계산출DDDs화소수금액병대기진행배서、분석。결과：근3년래，아원호흡과사용적두포균소류항균약물적DDDs화소수금액균정상승추세；제3대두포균소사용적충류최다，차기DDDs화소수금액배서야거수위；제4대두포균소적DDDs화소수금액명현저우제3대화제2대두포균소。결론：아원호흡과사용두포균소류항균약물교합리，단응엄격공제제3대두포균소적용약지정，이제고료효、연완세균내약성적산생。
OBJECTIVE:To investigate the use of cephalosporin antibiotics in patients from the respiratory department of Beijing Zhongguancun Hospital ( hereinafter referred to as “our hospital”) .METHODS: The data including drug names , specifications , quantities etc of cephalosporin antibiotics used in patients from the respiratory department of our hospital from 2011 to 2013 were retrieved from hospital information system for analysis of DDDs and consumption sum and their order using DDDs analysis as recommended by WHO . RESULTS: Both DDDs and consumption sum of cephalosporins showed increasing tendency from 2011 to 2013 . The third-generation cephalosporins were predominantly used and it took the lead in both DDDs and consumption sum .The DDDs and consumption sum of the fourth-generation cephalosporin antibiotics were significantly lower than those of the third -generation or second-generation cephalosporin antibiotics .CONCLUSIONS: The use of cephalosporin antibiotics in patients from the respiratory department of our hospital was rational .However , the medication indications of the third-generation cephalosporin antibiotics should be strictly controlled in order to improve the drug efficacy and delay the presence of bacterial drug resistance .