CAJ | 학술논문

目的：探讨原发性阑尾黏液腺癌的临床病理特征。方法对2例原发性阑尾黏液腺癌进行临床、组织学和免疫组化观察，并复习相关文献。结果2例阑尾黏液腺癌发病年龄均为60岁以上，临床症状酷似慢性阑尾炎。形态学表现为分化好的黏液上皮性病灶，上皮细胞立方或柱状，核位于基底，胞浆透亮，腺腔充满胶冻状黏液。免疫表型：瘤细胞CK（+）、EMA（+）、CK20（+）、Ki-67（+）、CK7（-）、Ch-A（-）、Syn（-）。结论原发性阑尾黏液腺癌是临床少见肿瘤，易被临床医师误诊为阑尾炎，确定原发诊断较困难，根据组织学形态和免疫组化表型可确诊。
목적：탐토원발성란미점액선암적림상병리특정。방법대2례원발성란미점액선암진행림상、조직학화면역조화관찰，병복습상관문헌。결과2례란미점액선암발병년령균위60세이상，림상증상혹사만성란미염。형태학표현위분화호적점액상피성병조，상피세포립방혹주상，핵위우기저，포장투량，선강충만효동상점액。면역표형：류세포CK（+）、EMA（+）、CK20（+）、Ki-67（+）、CK7（-）、Ch-A（-）、Syn（-）。결론원발성란미점액선암시림상소견종류，역피림상의사오진위란미염，학정원발진단교곤난，근거조직학형태화면역조화표형가학진。
Objective To study the clinical and pathological features of primary appendiceal mucinous adenocarcinoma. Methods 2 cases of primary appendiceal mucinous adenocarcinoma were observed about histology, immunohisto and chemistry, and reviewed the related literature. Results The age of onset of the appendiceal mucinous adenocarcinoma were both 60 and above, clinical symptoms liked chronic appendicitis. The morphology of the lesions appeared as good differentiation mucinous epithelial, cuboidal or columnar epithelial cells, nuclear was in the basal, cytoplasm was translucent, glandular cavity was filled with jelly mucus. Immunophenotyping:cancer cell CK(+), EMA(+), CK20(+), Ki-67(+), CK7(-), Ch-A(-), Syn(-). Conclusion Primary appendix mucinous adenocarcinoma is a rare tumor in clinical, easily by clinicians misdiagnosed as appendicitis, identify the primary diagnosis is difficult, according to the, histological appearance and immunohistochemical phenotype can be diagnosed.