CAJ | 학술논문

目的：探讨益气通络补肾汤治疗气虚血瘀型不典型膜性肾病的临床疗效。方法将80例不典型膜性肾病患者随机分为对照组40例，给予糖皮质激素，免疫抑制剂及改善循环药物；治疗组40例，在对照组的基础上加益气通络补肾汤；观察两组疗效及24h尿蛋白定量、血清白蛋白（ALB）、胆固醇（TC）、三酰甘油（TG）等指标的改善。结果治疗组治愈率及总有效率（20.0%，92.5%）明显高于对照组（7.5%，70.0%），差异有统计学意义（x2=7.601，P＜0.05）；治疗组实验室指标的改善均优于对照组，两组间治疗后比较差异有统计学意义（t1=15.81，t2=-2.14，t3=-3.03，t4=-2.01，P＜0.05）。结论益气通络补肾汤可明显提高气虚血瘀型不典型膜性肾病的临床疗效。
목적：탐토익기통락보신탕치료기허혈어형불전형막성신병적림상료효。방법장80례불전형막성신병환자수궤분위대조조40례，급여당피질격소，면역억제제급개선순배약물；치료조40례，재대조조적기출상가익기통락보신탕；관찰량조료효급24h뇨단백정량、혈청백단백（ALB）、담고순（TC）、삼선감유（TG）등지표적개선。결과치료조치유솔급총유효솔（20.0%，92.5%）명현고우대조조（7.5%，70.0%），차이유통계학의의（x2=7.601，P＜0.05）；치료조실험실지표적개선균우우대조조，량조간치료후비교차이유통계학의의（t1=15.81，t2=-2.14，t3=-3.03，t4=-2.01，P＜0.05）。결론익기통락보신탕가명현제고기허혈어형불전형막성신병적림상료효。
Objective To investigate the clinical efficacy of Yiqitongluo kidney soup in atypical membranous nephropathy with Qi deficiency and blood stasis. Methods 80 cases with atypical membranous nephropathy were randomly divided into a control group with 40 patients who received corticosteroids, immunosuppressants and drugs of circulation improved;the treatment group, with 40 cases, further received Yiqitongluo kidney soup;The efficacy of the two groups and 24 hours urinary protein excretion, serum albumin (ALB) cholesterol (TC), and improve of triglyceride (TG) and other indicators were observed. Results The cure rate in the treatment group and the overall response rate (20.0%, 92.5%) was significantly higher (7.5%, 70.0%), the difference was statistically significant (x2=7.601,P<0.05);laboratory indicators improvement in the treatment group was better than that in the control group, after treatment between the two groups were compared, t1=15.81, t2 = -2.14, t3=-3.03, t4=-2.01,the difference was statistically significant(P < 0.05). Conclusion Yiqitongluo soup can significantly improve clinical efficacy of treating kidney atypical membranous nephropathy with Qi deficiency and blood stasis.