CAJ | 학술논문

为了开发新型烟用香料，将烟酸与各种香味醇合成3-吡啶甲酸酯添加到卷烟中，并对其卷烟加香效果进行评价。以3-吡啶甲酸和一系列具有香味的醇为原料，经酰氯化反应先制成3-吡啶甲酰氯，再与香味醇回流反应生成3-吡啶甲酸酯类衍生物。所有化合物结构均经1 H NMR、13 C NMR、IR 和 HRMS 得到确证。对目标产物进行卷烟加香评吸，评吸结果表明，与对照卷烟相比，加入各种3-吡啶甲酸酯类衍生物的卷烟香气质改善，香气量增加，达到烟香协调、余味净化、杂气减轻的效果。合成的新型吡啶酯类衍生物将有可能作为香原料应用到卷烟中。
위료개발신형연용향료，장연산여각충향미순합성3-필정갑산지첨가도권연중，병대기권연가향효과진행평개。이3-필정갑산화일계렬구유향미적순위원료，경선록화반응선제성3-필정갑선록，재여향미순회류반응생성3-필정갑산지류연생물。소유화합물결구균경1 H NMR、13 C NMR、IR 화 HRMS 득도학증。대목표산물진행권연가향평흡，평흡결과표명，여대조권연상비，가입각충3-필정갑산지류연생물적권연향기질개선，향기량증가，체도연향협조、여미정화、잡기감경적효과。합성적신형필정지류연생물장유가능작위향원료응용도권연중。
In order to develop new cigarette flavors,the sensory evaluation of cigarettes added with 3-pyridinecarboxylic acid esters were conducted,which were synthesized from 3-pyridinecarboxylic acid and some scented alcohols.Taking 3-pyridinecar-boxylic acid and a series of scented alcohols as raw materials,3-pyridine carbonyl chloride was obtained through acylation reac-tion,then 3-pyridinecarboxylic acid ester derivatives were obtained via refluxing reaction from scented alcohols.All the struc-tures of obtained compounds were characterized by 1 H NMR,13 C NMR,IR and HRMS spectra.The results of tobacco flavor-ing experiments on these target products showed that,compared with controls,3-pyridinecarboxylic acid ester derivatives pre-cursor could improve the smoking quality,increase the aroma quantity,harmonize the aroma,clean the after-taste and reduce offensive odor of cigarettes.The synthesized 3-pyridinecarboxylic acid ester derivatives would be used as flavor materials in cig-arette flavoring.