CAJ | 학술논문

目的：研究特发性肺纤维化( IPF)患者的肺功能与螺旋CT影像学诊断的相关性。方法分析40例临床诊断IPF患者的肺功能和螺旋CT检查结果。入选的所有病例均在1周之内行肺功能测定和胸部CT扫描。结果螺旋CT的磨玻璃样密度影与一秒末用力呼气率( FEV1/FVC)有负相关性(轻度)；弥漫性线网状阴影与一氧化碳弥散量( DLco)和一氧化碳弥散率( DLco/VA)有显著负相关性；蜂窝影与FVC、FEV1、TLC、DLco和DLco/VA均具有一定的负相关性。结论不同程度的IPF患者肺功能参数与螺旋CT影像学征象存在一定的相关性。两种检查方法联合应用对于提高临床工作中IPF检出率及预测IPF的进展、预后及疗效有一定参考价值。
목적：연구특발성폐섬유화( IPF)환자적폐공능여라선CT영상학진단적상관성。방법분석40례림상진단IPF환자적폐공능화라선CT검사결과。입선적소유병례균재1주지내행폐공능측정화흉부CT소묘。결과라선CT적마파리양밀도영여일초말용력호기솔( FEV1/FVC)유부상관성(경도)；미만성선망상음영여일양화탄미산량( DLco)화일양화탄미산솔( DLco/VA)유현저부상관성；봉와영여FVC、FEV1、TLC、DLco화DLco/VA균구유일정적부상관성。결론불동정도적IPF환자폐공능삼수여라선CT영상학정상존재일정적상관성。량충검사방법연합응용대우제고림상공작중IPF검출솔급예측IPF적진전、예후급료효유일정삼고개치。
Objective To analyze the correlation between pulmonary function test and helical CT radiological diagnosis in idiopathic pulmonary fibrosis ( IPF) . Methods Helical CT scan was performed in 40 cases with idio-pathic pulmonary fibrosis. Pulmonary function test for each patient was performed within one week before or after CT scan. Results Ground-glass opacities were weak but significantly negatively correlated with FEV1/FVC. The signifi-cant negative correlation was found between reticular pattern and DLco, DLco/VA. Honeycombing was significantly negatively correlated with FVC, FEV1 , TLC, DLco and DLco/VA. Conclusion There is some correlation between pulmonary function test results and helical CT radiological signs. Pulmonary function test combined with CT scan can conduce to the diagnosis of IPF, and may calculate the progression, prognosis and response to treatment.