CAJ | 학술논문

目的：探讨慢性阻塞性肺疾病(简称慢阻肺)伴意识障碍患者的病情程度与动脉血气参数之间的关系。方法90例慢阻肺患者根据意识障碍程度分为清醒组、嗜睡组和昏迷组,对照组为30例健康体检者。分别测定各组患者及对照组的动脉血气指标及电解质。结果与对照组相比,慢阻肺患者pH值、动脉氧分压( PaO2)、血氧饱和度( SaO2)及氧合指数显著下降( P <0．05),二氧化碳分压( PaCO2)、碳酸氢盐(HCO3-)则显著升高(P<0．05),且出现Na+、CL-、K+降低(P<0．05)；随着意识障碍程度加重,清醒组、嗜睡组和昏迷组PaCO2、HCO-递增,pH值、PaO2及SaO2及氧合指数递减,Na+、CL-、K+也呈递减水平( P<0．05)。结论动脉血气参数变化可以反映慢阻肺患者意识障碍程度,随着动脉血气酸碱平衡紊乱加重,患者意识障碍程度加深。
목적：탐토만성조새성폐질병(간칭만조폐)반의식장애환자적병정정도여동맥혈기삼수지간적관계。방법90례만조폐환자근거의식장애정도분위청성조、기수조화혼미조,대조조위30례건강체검자。분별측정각조환자급대조조적동맥혈기지표급전해질。결과여대조조상비,만조폐환자pH치、동맥양분압( PaO2)、혈양포화도( SaO2)급양합지수현저하강( P <0．05),이양화탄분압( PaCO2)、탄산경염(HCO3-)칙현저승고(P<0．05),차출현Na+、CL-、K+강저(P<0．05)；수착의식장애정도가중,청성조、기수조화혼미조PaCO2、HCO-체증,pH치、PaO2급SaO2급양합지수체감,Na+、CL-、K+야정체감수평( P<0．05)。결론동맥혈기삼수변화가이반영만조폐환자의식장애정도,수착동맥혈기산감평형문란가중,환자의식장애정도가심。
Objective To investigate the relationship between severity and arterial blood gas parameters in patients with COPD merging conscious disturbance. Methods According to various degree of conscious disturbance, 90 patients with COPD were divided into the awake group, the somnolent group and the stuporous group. Another 30 healthy people were taken as the control group. The indexes of arterial blood gas and electrolyte in COPD patients and the control group were determined. Results Compared with the control group, the value of pH, PaO2 , SaO2 and ox-ygenation index decreased significantly in COPD patients ( P<0. 05 ) , while the levels of PaCO2 and HCO3 - in-creased significantly (P<0. 05). At the same time, there was a low level of Na+, CL- and K+ in COPD patients (P<0. 05). As anemia worsened, the levels of PaCO2 and HCO3 - were incremental, but the value of pH, PaO2, SaO2 and oxygenation index were diminishing in the awake group, the somnolent group and the stuporous group ( P<0. 05). And the levels of Na+, CL- and K+ decreased gradually (P<0. 05). Conclusion The change of arterial blood gas parameter can reflect the degree of conscious disturbance in COPD patients. With the development of arteri-al blood gas acid-base balance disorders increases, the degree of disturbance of consciousness deepens.