临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2015年
3期
528-529,530
,共3页
儿科%心衰%肺炎%血浆脑钠肽(BNP)
兒科%心衰%肺炎%血漿腦鈉肽(BNP)
인과%심쇠%폐염%혈장뇌납태(BNP)
pediatrics%heart failure%pneumonia%brain natriuretic peptide(BNP)
目的：探讨小儿肺炎合并心力衰竭患者血浆脑钠肽( BNP)测定在鉴别诊断和疗效评估中的价值。方法选择2012年8月至2014年2月入住我院的80例1-3岁肺炎患者，其中单纯肺炎病例46例和肺炎合并心衰病例34例。每位患者分别在入组时和治愈出院前进行血浆BNP的测定，另取20名健康体检同年龄段儿童测定血浆BNP作为健康对照。将检测结果进行入组时单纯肺炎组与肺炎合并心衰组比较、肺炎合并心衰组治疗前后比较。结果肺炎合并心衰组入院时的血浆BNP (750±120 pg/ml )高于单纯肺炎组(135±50 pg/ml)，差异有统计学意义(P<0．05)。肺炎合并心衰组患者治愈出院时的血浆BNP(85±45pg/ml)低于入组时(750±120 pg/ml)，差异也有统计学意义(P<0．05)。结论血浆BNP是小儿肺炎合并心力衰竭患者临床诊断及监测疗效的一个敏感性指标，对于临床诊疗具有重要应用价值。
目的：探討小兒肺炎閤併心力衰竭患者血漿腦鈉肽( BNP)測定在鑒彆診斷和療效評估中的價值。方法選擇2012年8月至2014年2月入住我院的80例1-3歲肺炎患者，其中單純肺炎病例46例和肺炎閤併心衰病例34例。每位患者分彆在入組時和治愈齣院前進行血漿BNP的測定，另取20名健康體檢同年齡段兒童測定血漿BNP作為健康對照。將檢測結果進行入組時單純肺炎組與肺炎閤併心衰組比較、肺炎閤併心衰組治療前後比較。結果肺炎閤併心衰組入院時的血漿BNP (750±120 pg/ml )高于單純肺炎組(135±50 pg/ml)，差異有統計學意義(P<0．05)。肺炎閤併心衰組患者治愈齣院時的血漿BNP(85±45pg/ml)低于入組時(750±120 pg/ml)，差異也有統計學意義(P<0．05)。結論血漿BNP是小兒肺炎閤併心力衰竭患者臨床診斷及鑑測療效的一箇敏感性指標，對于臨床診療具有重要應用價值。
목적：탐토소인폐염합병심력쇠갈환자혈장뇌납태( BNP)측정재감별진단화료효평고중적개치。방법선택2012년8월지2014년2월입주아원적80례1-3세폐염환자，기중단순폐염병례46례화폐염합병심쇠병례34례。매위환자분별재입조시화치유출원전진행혈장BNP적측정，령취20명건강체검동년령단인동측정혈장BNP작위건강대조。장검측결과진행입조시단순폐염조여폐염합병심쇠조비교、폐염합병심쇠조치료전후비교。결과폐염합병심쇠조입원시적혈장BNP (750±120 pg/ml )고우단순폐염조(135±50 pg/ml)，차이유통계학의의(P<0．05)。폐염합병심쇠조환자치유출원시적혈장BNP(85±45pg/ml)저우입조시(750±120 pg/ml)，차이야유통계학의의(P<0．05)。결론혈장BNP시소인폐염합병심력쇠갈환자림상진단급감측료효적일개민감성지표，대우림상진료구유중요응용개치。
Objective To investigate the differential diagnostic and therapeutic values of plasma brain natri-uretic peptide ( BNP) assay in children′s pneumonia complicated with heart failure. Methods The clinical data of 80 1-3 years old children with pneumonia were analyzed. They were divided into two groups, the simple pneumonia group (46 cases) and the pneumonia complicated with heart failure group (34 cases). All patients underwent twice plasma BNP assay:first on admission into hospital and second before discharge. Besides, 20 healthy children′s plas-ma BNP level were also detected as the control group. The plasma level of BNP was compared between the two groups. Results The plasma level of BNP was higher in the pneumonia complicated with heart failure group than that in the simple pneumonia group on admission (750 ± 120 vs 135 ± 50 pg/ml) (P<0. 05). In the pneumonia ac-companied with heart failure group, the plasma level of BNP was higher when they were admitted to hospital than dis-charged (750 ± 120 vs 85 ± 45 pg/ml) (P<0. 05). Conclusion Plasma BNP is a sensitive diagnostic and thera-peutic evaluative marker for children with pneumonia accompanied with heart failure, which is important to clinical diagnosis and treatment.
