CAJ | 학술논문

目的：观察前列地尔对进展性缺血性脑卒中患者的影响。方法选取我院神经内科2009‐08—2013‐08治疗的200例经头部 C T或 M RI证实的首次卒中者。随机数字表法分为实验组和对照组，实验组使用前列地尔（0.9％氯化钠注射液50 mL＋前列地尔注射液10μg）治疗，对照组使用安慰剂（0.9％氯化钠注射液50 mL＋10％脂肪乳注射液1 mL）治疗，比较2组治疗后SIP的发生率。结果根据欧洲卒中研究小组对进展性脑卒中的评定标准，对照组 SIP发生率39％明显高于实验组21％，差异有统计学意义（ P＜0.05）。结论前列地尔在预防和减少进展性脑卒中的发生风险具有明显的效果，值得临床推广使用。
목적：관찰전렬지이대진전성결혈성뇌졸중환자적영향。방법선취아원신경내과2009‐08—2013‐08치료적200례경두부 C T혹 M RI증실적수차졸중자。수궤수자표법분위실험조화대조조，실험조사용전렬지이（0.9％록화납주사액50 mL＋전렬지이주사액10μg）치료，대조조사용안위제（0.9％록화납주사액50 mL＋10％지방유주사액1 mL）치료，비교2조치료후SIP적발생솔。결과근거구주졸중연구소조대진전성뇌졸중적평정표준，대조조 SIP발생솔39％명현고우실험조21％，차이유통계학의의（ P＜0.05）。결론전렬지이재예방화감소진전성뇌졸중적발생풍험구유명현적효과，치득림상추엄사용。
Objective To investigate the curative effect of Alprostadil on preventing patients with progressive‐ischemic stroke. Methods 200 first stroke patients confirmed by head CT or MRI in our hospital from August 2009 to August 2013 were divided into control group (treated with placebo) and experimental group (treated with alprostadil). The progressive‐is‐chemic stroke incidence of two groups was compared. Results The progressive‐ischemic stroke incidence of control group was higher than that of experimental group (39% vs 21% ). Conclusion Alprostadil can obviously prevent or reduce the risk occur‐rence of patients progressive‐ischemic stroke ,which is worthy of application.