中国实用神经疾病杂志
中國實用神經疾病雜誌
중국실용신경질병잡지
CHINESE JOURNAL OF PRACTICAL NERVOUS DISEASES
2015年
2期
14-15
,共2页
儿童%多发性抽动症%丙戊酸钠
兒童%多髮性抽動癥%丙戊痠鈉
인동%다발성추동증%병무산납
Children%Tourette%Valproate
目的：探讨丙戊酸钠治疗儿童多发性抽动症的疗效。方法将68例多发性抽动症患儿随机分为观察组和对照组，对照组给予氟哌啶醇治疗，观察组给予丙戊酸钠治疗，比较2组治疗总有效率、运动抽动及发声抽动评分及不良反应发生情况。结果2组总有效比较差异无统计学意义（ P＞0.05）。观察组治疗后8周后运动抽动及发声抽动评分均优于对照组，差异有统计学意义（P＜0.05）。2组不良反应发生情况相当（P＞0.05）。结论丙戊酸钠对儿童多发性抽动症的疗效较好，可有效改善患儿运动抽动及发声抽动症状，且不良反应较小，值得临床推广。
目的：探討丙戊痠鈉治療兒童多髮性抽動癥的療效。方法將68例多髮性抽動癥患兒隨機分為觀察組和對照組，對照組給予氟哌啶醇治療，觀察組給予丙戊痠鈉治療，比較2組治療總有效率、運動抽動及髮聲抽動評分及不良反應髮生情況。結果2組總有效比較差異無統計學意義（ P＞0.05）。觀察組治療後8週後運動抽動及髮聲抽動評分均優于對照組，差異有統計學意義（P＜0.05）。2組不良反應髮生情況相噹（P＞0.05）。結論丙戊痠鈉對兒童多髮性抽動癥的療效較好，可有效改善患兒運動抽動及髮聲抽動癥狀，且不良反應較小，值得臨床推廣。
목적：탐토병무산납치료인동다발성추동증적료효。방법장68례다발성추동증환인수궤분위관찰조화대조조，대조조급여불고정순치료，관찰조급여병무산납치료，비교2조치료총유효솔、운동추동급발성추동평분급불량반응발생정황。결과2조총유효비교차이무통계학의의（ P＞0.05）。관찰조치료후8주후운동추동급발성추동평분균우우대조조，차이유통계학의의（P＜0.05）。2조불량반응발생정황상당（P＞0.05）。결론병무산납대인동다발성추동증적료효교호，가유효개선환인운동추동급발성추동증상，차불량반응교소，치득림상추엄。
Objective To investigate the curative effect of valproate on treating children with tourette.Methods 68 chil‐dren with tourette were randomly divided into observation group (treated with sodium valproate) and control group (treated with haloperidol). The total efficiency ,motor tics and vocaltic score and adverse reaction of two groups were compared.Results The total efficiency and adverse reaction of two groups had no statisticaldifference. The motor tics and vocaltic score of ob‐servation group were better than these of control group.Conclusion Valproate has better curative effect on treating children with tourette ,which can effectively improve the symptom of motor tics and vocaltics and have lower adverse reaction to be worthy of application.
