中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2015年
2期
40-41
,共2页
急性有机磷中毒%洗胃%胆碱酯酶复能剂%阿托品%治疗
急性有機燐中毒%洗胃%膽堿酯酶複能劑%阿託品%治療
급성유궤린중독%세위%담감지매복능제%아탁품%치료
Acute organophosphate poisoning%Lavage%Cholinesterase agents%Atropine%Treatment
目的：在相应的季节及年龄段加强有机磷中毒的筛查，提高有机磷中毒的救治水平，减少病死率。方法统计分析我院2007年1月至2012年12月的急性有机磷中毒患者403例，对临床资料进行回顾性分析。结果139例收急诊留观，76例收住急诊病房，128例收住于急诊ICU及ICU，转上级医院20例，16例死亡，其中治愈出院337例，病死率3.9%，9例出现反跳现象及中间综合征。结论有机磷中毒具有明显的季节性（夏季及秋季），有明显的年龄差异，中毒后应尽快送入急诊，脱离中毒环境或彻底洗胃减少毒物吸收，尽早、足量的使用胆碱酯酶复能剂和阿托品；快速地达到阿托品化，根据病情变化及时调整阿托品用量，警惕阿托品中毒的发生，才能减少并发症，同时应强调综合治疗及心理干预。这样才能有效地提高治愈率降低病死率。
目的：在相應的季節及年齡段加彊有機燐中毒的篩查，提高有機燐中毒的救治水平，減少病死率。方法統計分析我院2007年1月至2012年12月的急性有機燐中毒患者403例，對臨床資料進行迴顧性分析。結果139例收急診留觀，76例收住急診病房，128例收住于急診ICU及ICU，轉上級醫院20例，16例死亡，其中治愈齣院337例，病死率3.9%，9例齣現反跳現象及中間綜閤徵。結論有機燐中毒具有明顯的季節性（夏季及鞦季），有明顯的年齡差異，中毒後應儘快送入急診，脫離中毒環境或徹底洗胃減少毒物吸收，儘早、足量的使用膽堿酯酶複能劑和阿託品；快速地達到阿託品化，根據病情變化及時調整阿託品用量，警惕阿託品中毒的髮生，纔能減少併髮癥，同時應彊調綜閤治療及心理榦預。這樣纔能有效地提高治愈率降低病死率。
목적：재상응적계절급년령단가강유궤린중독적사사，제고유궤린중독적구치수평，감소병사솔。방법통계분석아원2007년1월지2012년12월적급성유궤린중독환자403례，대림상자료진행회고성분석。결과139례수급진류관，76례수주급진병방，128례수주우급진ICU급ICU，전상급의원20례，16례사망，기중치유출원337례，병사솔3.9%，9례출현반도현상급중간종합정。결론유궤린중독구유명현적계절성（하계급추계），유명현적년령차이，중독후응진쾌송입급진，탈리중독배경혹철저세위감소독물흡수，진조、족량적사용담감지매복능제화아탁품；쾌속지체도아탁품화，근거병정변화급시조정아탁품용량，경척아탁품중독적발생，재능감소병발증，동시응강조종합치료급심리간예。저양재능유효지제고치유솔강저병사솔。
Objective To strengthen the screening of organophosphorus pesticide poisoning in the season and age appropriate, to raise the level of the treatment of organic phosphorus poisoning, reduce the death rate. Methods Statistical analysis of acute organic phosphorus in our hospital from January 2007 to December 2012 403 cases of poisoning, the clinical data were analyzed retrospectively. Results 139 cases received emergency observation, 76 patients admitted to the emergency ward, 128 patients admitted to the emergency ICU and ICU, turn the hospital in 20 cases, 16 cases died, in which 337 cases were cured, 9 cases with a mortality rate of 3.9%, appeared to rebound and intermediate syndrome. Conclusion Organic phosphorus poisoning have obvious seasonal(summer and autumn), have signiifcant age differences, poisoning as soon as possible after admitted to emergency, from poisoning the environment or gastric lavage completely reduce the absorption of toxicant, early, adequate use of cholinesterase reactivator and atropine;quickly reach atropinization, timely adjust according to the illness change of dosage of atropine, wary of atropine poisoning, can reduce the complications, should be emphasized that the comprehensive treatment and psychological intervention. This can effectively improve the cure rate of mortality.
