微生物学免疫学进展
微生物學免疫學進展
미생물학면역학진전
PROGRESS IN MICROBIOLOGY AND IMMUNOLOGY
2015年
2期
30-34
,共5页
袁莉凤%徐沛兰%何燕梅%陈达婵
袁莉鳳%徐沛蘭%何燕梅%陳達嬋
원리봉%서패란%하연매%진체선
疑似预防接种异常反应%监测%疫苗接种%分析
疑似預防接種異常反應%鑑測%疫苗接種%分析
의사예방접충이상반응%감측%역묘접충%분석
Adverse effects following immunization(AEFI)%Monitoring%Vaccination%Analysis
目的：分析藤县2010—2013年疑似预防接种异常反应（AEFI）发生特征，评价 AEFI 监测系统运行情况，评价预防接种疫苗的安全性。方法通过疑似预防接种异常反应信息管理系统，收集整理藤县2010—2013年报告疑似预防接种异常反应个案数据，采用描述性方法进行流行病学分析。结果全县2010—2013年共报告 AEFI 个案86例，AEFI 发生率6．34／10万，其中异常反应80例，占93．02％；一般反应5例，占5．81％，偶合反应1例，占1．16％；无疫苗质量事故、接种事故、心因性反应、不明原因、待定报告。24 h 内报告率占90．7％，及时调查率达到100％。AEFI 报告个案中＜1岁儿童占94．17％，男、女比例为2．44∶1，多发生在接种15天后，没有明显的季节性、聚集性，所涉及的疫苗有8种。结论AEFI 监测系统运转正常，所使用的疫苗安全性和预防接种服务质量均良好，但监测质量有待进一步提高，需加强对一般反应的监测。
目的：分析籐縣2010—2013年疑似預防接種異常反應（AEFI）髮生特徵，評價 AEFI 鑑測繫統運行情況，評價預防接種疫苗的安全性。方法通過疑似預防接種異常反應信息管理繫統，收集整理籐縣2010—2013年報告疑似預防接種異常反應箇案數據，採用描述性方法進行流行病學分析。結果全縣2010—2013年共報告 AEFI 箇案86例，AEFI 髮生率6．34／10萬，其中異常反應80例，佔93．02％；一般反應5例，佔5．81％，偶閤反應1例，佔1．16％；無疫苗質量事故、接種事故、心因性反應、不明原因、待定報告。24 h 內報告率佔90．7％，及時調查率達到100％。AEFI 報告箇案中＜1歲兒童佔94．17％，男、女比例為2．44∶1，多髮生在接種15天後，沒有明顯的季節性、聚集性，所涉及的疫苗有8種。結論AEFI 鑑測繫統運轉正常，所使用的疫苗安全性和預防接種服務質量均良好，但鑑測質量有待進一步提高，需加彊對一般反應的鑑測。
목적：분석등현2010—2013년의사예방접충이상반응（AEFI）발생특정，평개 AEFI 감측계통운행정황，평개예방접충역묘적안전성。방법통과의사예방접충이상반응신식관리계통，수집정리등현2010—2013년보고의사예방접충이상반응개안수거，채용묘술성방법진행류행병학분석。결과전현2010—2013년공보고 AEFI 개안86례，AEFI 발생솔6．34／10만，기중이상반응80례，점93．02％；일반반응5례，점5．81％，우합반응1례，점1．16％；무역묘질량사고、접충사고、심인성반응、불명원인、대정보고。24 h 내보고솔점90．7％，급시조사솔체도100％。AEFI 보고개안중＜1세인동점94．17％，남、녀비례위2．44∶1，다발생재접충15천후，몰유명현적계절성、취집성，소섭급적역묘유8충。결론AEFI 감측계통운전정상，소사용적역묘안전성화예방접충복무질량균량호，단감측질량유대진일보제고，수가강대일반반응적감측。
Objective To analyse the characteristics of adverse events following immunization (AEFI)in 2010 to 2013 in Tengxian,and to evaluate operation condition for monitoring system of AEFI and the safety for vaccination.Methods Through information management system,to collect reported data for AEFI cases in 2010 to 2013 in Tengxian,and analysis of the data by means of the descriptive epidemiology.Results Total of 86 AEFI cases were reported from 2010 to 2013, the incidence rate of AEFI was 6.34 /105 ,including abnormal reaction in 80 cases,accounted for 93.02%;The general reaction in 5 cases,accounted for 5.81%,the coupling reaction in 1 case,accounted for 1.16%;There was no vaccine quality accident,failure of vaccine inoculation,psychogenic reaction,unknown causes,and pending reports.The reported cases within 24 h accounted for 90.7%,and the timely investigation reached 100%.AEFI cases in less than one year old children was 94.17%,the ratio of male and female was 2.44 ∶1,AEFI occured in and more than 15 d after inoculation, and there was no obvious seasonal accumulation,involved 8 kinds of vaccines.Conclusion The AEFI monitoring system was operating in a normal mode,and the safety of vaccination and vaccination service quality was good,but the quality of monitoring needs to be further improved and the general reaction for monitoring strengthened too.
