中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2015年
2期
4-5
,共2页
陈颢予%徐晓红%蒋成鹏%王宝林
陳顥予%徐曉紅%蔣成鵬%王寶林
진호여%서효홍%장성붕%왕보림
儿童过敏性紫癜%幽门螺旋杆菌%相关性
兒童過敏性紫癜%幽門螺鏇桿菌%相關性
인동과민성자전%유문라선간균%상관성
Children allergic purpura%Helicobacter pylori%Relevance
目的：研究儿童过敏性紫癜（HSP）与幽门螺旋杆菌（HP）感染的相关性。方法选择从2011年5月至2013年9月于我院确诊的70例腹型过敏性紫癜患儿作为试验组，另选择60例健康小儿作为对照组，试验组患儿和对照组均采用尿素14C呼气检测方法检查HP感染情况，对试验组HP感染阳性患儿行胃镜检查，观察胃、十二指肠等病变情况。结果试验组的HP感染率65.7%，而对照组的HP感染率30.0%，两组HP感染率比较，差异有统计学意义（χ2=16.4874，P=0.0000），试验组18例HP感染阳性的患者中，17例患者在胃镜活检下发现胃黏膜病变，1例在胃镜活检下未发现黏膜病变。黏膜病变多表现为散在片状出血斑、糜烂出血等。发现十二指肠球部、降部病变发生率最高，胃窦、胃体其次、剩下依次为十二指肠水平部、胃底。结论 HP感染与儿童HSP发病有一定的相关性，HP感染阳性的HSP患儿存在不同程度的胃十二指肠黏膜病变情况。
目的：研究兒童過敏性紫癜（HSP）與幽門螺鏇桿菌（HP）感染的相關性。方法選擇從2011年5月至2013年9月于我院確診的70例腹型過敏性紫癜患兒作為試驗組，另選擇60例健康小兒作為對照組，試驗組患兒和對照組均採用尿素14C呼氣檢測方法檢查HP感染情況，對試驗組HP感染暘性患兒行胃鏡檢查，觀察胃、十二指腸等病變情況。結果試驗組的HP感染率65.7%，而對照組的HP感染率30.0%，兩組HP感染率比較，差異有統計學意義（χ2=16.4874，P=0.0000），試驗組18例HP感染暘性的患者中，17例患者在胃鏡活檢下髮現胃黏膜病變，1例在胃鏡活檢下未髮現黏膜病變。黏膜病變多錶現為散在片狀齣血斑、糜爛齣血等。髮現十二指腸毬部、降部病變髮生率最高，胃竇、胃體其次、剩下依次為十二指腸水平部、胃底。結論 HP感染與兒童HSP髮病有一定的相關性，HP感染暘性的HSP患兒存在不同程度的胃十二指腸黏膜病變情況。
목적：연구인동과민성자전（HSP）여유문라선간균（HP）감염적상관성。방법선택종2011년5월지2013년9월우아원학진적70례복형과민성자전환인작위시험조，령선택60례건강소인작위대조조，시험조환인화대조조균채용뇨소14C호기검측방법검사HP감염정황，대시험조HP감염양성환인행위경검사，관찰위、십이지장등병변정황。결과시험조적HP감염솔65.7%，이대조조적HP감염솔30.0%，량조HP감염솔비교，차이유통계학의의（χ2=16.4874，P=0.0000），시험조18례HP감염양성적환자중，17례환자재위경활검하발현위점막병변，1례재위경활검하미발현점막병변。점막병변다표현위산재편상출혈반、미란출혈등。발현십이지장구부、강부병변발생솔최고，위두、위체기차、잉하의차위십이지장수평부、위저。결론 HP감염여인동HSP발병유일정적상관성，HP감염양성적HSP환인존재불동정도적위십이지장점막병변정황。
Objective To analyze the correlation between Purpura in children and the infected with Helicobacter pylori. Methods 70 cases of allergic purpura in children were selected from May 2011 to September 2013 in our hospital as the test group, and the other 60 cases of healthy children as a control group, the experimental group and a control group of children were using 14C urea breath to check the HP infection, then the test group of HP infection were underwent endoscopy, and observed lesions of the stomach, duodenum and so on. Results The rate of HP infection in the test group was 65.7%, while that of the control group was 30.0%, comparison of the rate of the two HP infection,the difference was statistically signiifcant(χ2=16.4874, P=0.0000), patients with positive HP infection in test group were 18 patients, while 17 patients were found that gastric lesions in endoscopic biopsy, only 1 case were found no mucosal lesions in endoscopic biopsy. Mucosal lesions showed scattered lfakes bleeding spots, erosion and bleeding. Found duodenal descending lesions highest incidence of gastric antrum, body followed, and the rest were duodenum, gastric fundus. Conclusions HP infection and the HSP children have some relevance, HP positive infections in children with varying degrees of gastroduodenal mucosal lesions.
