黑龙江医药
黑龍江醫藥
흑룡강의약
HEILONGJIANG MEDICAL JOURNAL
2015年
1期
26-28,29
,共4页
肺动脉高压%分类%致病机制
肺動脈高壓%分類%緻病機製
폐동맥고압%분류%치병궤제
Pulmonary hypertension%classification%pathogenic mechanisms
肺动脉高压(PAH)是由不同致病机制导致的、以肺循环压力和肺血管阻力升高为主要特点，主要病理表现是血管收缩、血管重构和原位血栓的形成，最终导致右心负荷增大或心功能不全、肺血流量明显减少，严重影响患者生活质量和预后效果。近年来，PAH的研究在包括分类、致病机制、诊断和治疗等方面均有重大突破。为临床指导治疗肺动脉高压奠定了坚实的基础。
肺動脈高壓(PAH)是由不同緻病機製導緻的、以肺循環壓力和肺血管阻力升高為主要特點，主要病理錶現是血管收縮、血管重構和原位血栓的形成，最終導緻右心負荷增大或心功能不全、肺血流量明顯減少，嚴重影響患者生活質量和預後效果。近年來，PAH的研究在包括分類、緻病機製、診斷和治療等方麵均有重大突破。為臨床指導治療肺動脈高壓奠定瞭堅實的基礎。
폐동맥고압(PAH)시유불동치병궤제도치적、이폐순배압력화폐혈관조력승고위주요특점，주요병리표현시혈관수축、혈관중구화원위혈전적형성，최종도치우심부하증대혹심공능불전、폐혈류량명현감소，엄중영향환자생활질량화예후효과。근년래，PAH적연구재포괄분류、치병궤제、진단화치료등방면균유중대돌파。위림상지도치료폐동맥고압전정료견실적기출。
Pulmonary hypertension (PAH) is different pathogenic mechanisms leading to the lungs pulmonary circulation pressure and pulmonary vascular resistance increases as the main features of the main pathology is vasoconstriction, vascular remodeling and in situ thrombosis, eventually leading to right heart load increase large or heart failure, pulmonary blood flow was significantly reduced, seriously affecting the quality of life and prognosis of patients. In recent years, PAH studies include classification, pathogenesis, diag-nosis and treatment and other aspects are a major breakthrough. For the treatment of pulmonary arterial hypertension clinical guide-lines laid a solid foundation.
