CAJ | 학술논문

目的：探讨脑转移瘤的临床特点、手术疗效并分析预后。方法选择2006‐01—2014‐01本院诊治的60例脑转移瘤患者为研究对象。结果60例患者中单发病灶45例（75.0％），多发15例（25.0％）；原发病为肺癌35例（58.3％），乳腺癌8例（13.3％），其他恶性肿瘤17例（28.4％）；病灶周围水肿、环形强化及毛刷样征象是常见的影像学特点；60例患者1 a及2 a生存率分别为58.3％和18.3％；单因素分析显示：肿瘤数目、治疗方式、病灶大小与患者生存期相关（P＜0.05）；Cox模型多因素分析结果显示：治疗方式及肿瘤数目是影响患者生存期的独立因素。结论脑转移瘤原发病以肺癌为最常见。治疗方式及肿瘤数目是生存期的影响因素，手术联合放化疗治疗效果最理想。
목적：탐토뇌전이류적림상특점、수술료효병분석예후。방법선택2006‐01—2014‐01본원진치적60례뇌전이류환자위연구대상。결과60례환자중단발병조45례（75.0％），다발15례（25.0％）；원발병위폐암35례（58.3％），유선암8례（13.3％），기타악성종류17례（28.4％）；병조주위수종、배형강화급모쇄양정상시상견적영상학특점；60례환자1 a급2 a생존솔분별위58.3％화18.3％；단인소분석현시：종류수목、치료방식、병조대소여환자생존기상관（P＜0.05）；Cox모형다인소분석결과현시：치료방식급종류수목시영향환자생존기적독립인소。결론뇌전이류원발병이폐암위최상견。치료방식급종류수목시생존기적영향인소，수술연합방화료치료효과최이상。
Objective To investigate the clinical characteristics ,surgical curative effect and prognosis for patients with brain metastasis.Methods Sixty patients with brain metastasis from January 2006 to January 2014 were selected as research subjects.Results There were 45 cases of single occurred tumor (75.0% ) and 15 cases of multiple occurred tumor (25% ) in 60 patients. The primary disease of 60 patients was 35 cases of lung cancer (58.3% ) ,8 cases of cancer (13.3% ) and 17 cases of other malignant tumors. The common imaging characteristics of 60 patients were perilesional edema ,ring‐enhancement and brush‐like changes. The survival rates of 60 patients at 1 year and 2 years were 58.3% and 18.3% ,respectively. Single factor analysis results showed that the tumor number ,therapeutic method and lesion size were correlated with the survival rate of pa‐tients (P<0.05). Multivariate cox regression results showed that the tumor number and therapeutic methods were independ‐ence risk factors for survival rates.Conclusion Lung cancer is the most common primary disease for brain metastasis. The tumor number and therapeutic methods were independence risk factors for survival rates. Operation combined with chemo‐ra‐diotherapy has ideal effect on treating patients with brain metastasis.