CAJ | 학술논문

目的：基于文献与Logistic回归分析探讨中医治疗耳鸣用药规律。方法检索中国期刊全文数据库(CNKI,1984－2013年)、中文科技期刊数据库(VIP,1989－2013年)、中国生物医学文献数据库(CBM,1984－2013年)、中国学术期刊数据库(万方数据,1990－2013年)及PubMed(1984－2013年),对收录的关于中医治疗耳鸣的相关文献进行筛选,并对用药频次进行统计,采用Logistic多元逐步回归法对耳鸣分型用药进行模型建立。结果常用方使用频次较高的分别为六味地黄丸、龙胆泻肝汤和耳聋左慈丸。根据分型用药回归方程,并结合专业知识判断,肾气不足型耳鸣常用山萸肉、补骨脂、枸杞子；脾气亏虚型常用黄芪、白术、党参；肝失疏泄型常用栀子、龙胆、香附；痰火郁结型常用半夏、枳实、防己；风热外乘型常用连翘、薄荷、桑白皮。结论通过用药频次统计和Logistic多元逐步回归分析方法可为中医治疗耳鸣用药及临床辨证论治提供参考。
목적：기우문헌여Logistic회귀분석탐토중의치료이명용약규률。방법검색중국기간전문수거고(CNKI,1984－2013년)、중문과기기간수거고(VIP,1989－2013년)、중국생물의학문헌수거고(CBM,1984－2013년)、중국학술기간수거고(만방수거,1990－2013년)급PubMed(1984－2013년),대수록적관우중의치료이명적상관문헌진행사선,병대용약빈차진행통계,채용Logistic다원축보회귀법대이명분형용약진행모형건립。결과상용방사용빈차교고적분별위륙미지황환、룡담사간탕화이롱좌자환。근거분형용약회귀방정,병결합전업지식판단,신기불족형이명상용산유육、보골지、구기자；비기우허형상용황기、백술、당삼；간실소설형상용치자、룡담、향부；담화욱결형상용반하、지실、방기；풍열외승형상용련교、박하、상백피。결론통과용약빈차통계화Logistic다원축보회귀분석방법가위중의치료이명용약급림상변증론치제공삼고。
Objective To explore the rule of traditional Chinese medicine in treating tinnitus based on literature and Logistic multiple regression analysis. Methods Articles about tinnitus treatment using traditional Chinese medicine were searched in several databases, i.e. CNKI (1984-2013), VIP (1989-2013), CBM (1990-2013), and PubMed (1984-2013), and medication frequency was analyzed. Then, models for tinnitus medication were established through metrological method and Logistic multiple regression. Results The common prescriptions with highest frequency usage were Liuwei Dihuang Pill, Longdan Xiegan Decoction, and Erlong Zuoci Pill. Corni Fructus, Psoraleae Fructus, and Lycii Fructus were commonly used for kidney-deficiency type of tinnitus;Astragali Radix, Atractylodis Macrocephalae Rhizoma, and Codonopsis Radix were commonly used for the spleen-qi-deficiency type of tinnitus;Gardeniae Fructus, Gentianae Radix et Rhizoma, and Cyperi Rhizoma were commonly used for the liver-qi-dysfunction type of tinnitus;Pinelliae Rhizoma, Aurantii Fructus Immaturus, and Stephaniae Tetrandrae Radix were commonly used for the phlegm-fire disturbance type of tinnitus;Forsythiae Fructus, Menthae Haplocalycis Herba, and Mori Cortex were commonly used for the wind-fire-invasion type of tinnitus. Conclusion Analysis of medication frequency and Logistic multiple regression analysis can provide evidence and reference for the treatment of tinnitus and syndrome differentiation.