中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2015年
2期
73-75
,共3页
硫酸依替米星%头孢菌素%老年社区%获得性肺炎
硫痠依替米星%頭孢菌素%老年社區%穫得性肺炎
류산의체미성%두포균소%노년사구%획득성폐염
Sulfate etimicin%Cephalosporins%Elderly community%Acquired pneumonia
目的：探讨硫酸依替米星与头孢菌素联合治疗老年社区获得性肺炎的实效性评价。方法选取2013年1月~2014年1月我院收治的88例CAP患者,将其分为观察组和对照组,各44例。观察组患者采用头孢菌素联合硫酸依替米星治疗,而对照组单独使用头孢菌素进行治疗,并从细菌学、患者的体温、咳嗽和咳痰、血象变化、X线胸片变化、肾毒性及耳毒性等方面进行观察分析。结果经过治疗后,观察组和对照组有效率分别为81.8%和59.1%,两组存在显著差异﹙χ2=5.459,P=0.019<0.05)；观察组和对照组的细菌清除率分别为77.3%和47.2%,差异有统计学意义﹙χ2=8.194,P=0.004)；两组患者的肾毒性及耳毒性比较,差异有统计学意义﹙χ2=4.201,P<0.05；χ2=3.382,P<0.05)。结论硫酸依替米星和头孢菌素的联合使用对于细菌感染和病情的控制具有良好的治疗效果,是临床上可以考虑的一种有效手段,值得临床上大力推广。
目的：探討硫痠依替米星與頭孢菌素聯閤治療老年社區穫得性肺炎的實效性評價。方法選取2013年1月~2014年1月我院收治的88例CAP患者,將其分為觀察組和對照組,各44例。觀察組患者採用頭孢菌素聯閤硫痠依替米星治療,而對照組單獨使用頭孢菌素進行治療,併從細菌學、患者的體溫、咳嗽和咳痰、血象變化、X線胸片變化、腎毒性及耳毒性等方麵進行觀察分析。結果經過治療後,觀察組和對照組有效率分彆為81.8%和59.1%,兩組存在顯著差異﹙χ2=5.459,P=0.019<0.05)；觀察組和對照組的細菌清除率分彆為77.3%和47.2%,差異有統計學意義﹙χ2=8.194,P=0.004)；兩組患者的腎毒性及耳毒性比較,差異有統計學意義﹙χ2=4.201,P<0.05；χ2=3.382,P<0.05)。結論硫痠依替米星和頭孢菌素的聯閤使用對于細菌感染和病情的控製具有良好的治療效果,是臨床上可以攷慮的一種有效手段,值得臨床上大力推廣。
목적：탐토류산의체미성여두포균소연합치료노년사구획득성폐염적실효성평개。방법선취2013년1월~2014년1월아원수치적88례CAP환자,장기분위관찰조화대조조,각44례。관찰조환자채용두포균소연합류산의체미성치료,이대조조단독사용두포균소진행치료,병종세균학、환자적체온、해수화해담、혈상변화、X선흉편변화、신독성급이독성등방면진행관찰분석。결과경과치료후,관찰조화대조조유효솔분별위81.8%화59.1%,량조존재현저차이﹙χ2=5.459,P=0.019<0.05)；관찰조화대조조적세균청제솔분별위77.3%화47.2%,차이유통계학의의﹙χ2=8.194,P=0.004)；량조환자적신독성급이독성비교,차이유통계학의의﹙χ2=4.201,P<0.05；χ2=3.382,P<0.05)。결론류산의체미성화두포균소적연합사용대우세균감염화병정적공제구유량호적치료효과,시림상상가이고필적일충유효수단,치득림상상대력추엄。
Objective To investigate the solid effective evaluation of sulfate etimicin combined with cephalosporins for elderly patients with community-acquired pneumonia. Methods A total of 88 CAP patients were selected from January 2013 to January 2014 in our hospital were divided into observation group and control group with 44 patients respec-tively. Patients in observation group were treated with sulfate etimicin combined with cephalosporins while the control group was treat ed with cephalosporin alone. All patient’s bacteriology,patient's temperature,cough and sputum, changes in blood,X-ray changes, nephrotoxicity and ototoxicity were observed. Results After treatment, the efficient rate in the observation group was 81.8% while the efficient rate in control group was 59.1%.After compared between the two groups,it had a significant difference﹙χ2=5.459,P=0.019<0.05). The observation group and bacterial clearance rate in the control group were 77.3% and 47.2% and the difference was statistically significant ﹙χ2=8.194,P=0.004). After the comparison of nephrotoxicity and ototoxicity between two groups, there was a significant difference ﹙χ2=4.201,P<0.05; χ2=3.382,P<0.05). Conclusion Sulfate etimicin combined with cephalosporins has a good effect for the control of bacterial infection and the disease and it can be considered as a clinically and worthwhile effective means to promote clinical.
