中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
3期
29-30
,共2页
非小细胞肺癌症%同步三维适形%放疗%长春瑞滨
非小細胞肺癌癥%同步三維適形%放療%長春瑞濱
비소세포폐암증%동보삼유괄형%방료%장춘서빈
Non small cell lung cancer%Synchronous three dimensional conformal%Radiotherapy%Navelbine
目的：观察长春瑞滨与同步三维适形放疗联合治疗局部晚期非小细胞肺癌的有效性和安全性。方法：2010年5月-2013年9月收治局部晚期非小细胞肺癌患者136例，随机分为试验组和对照组，各68例，对照组给予长春瑞滨化疗，试验组在长春瑞滨化疗的基础上联合三维适形放疗。结果：试验组和对照组的平均随访期12.2个月，OS分别为17.2个月和15.7个月[HR0.975(95%CI 0.655，1.451；P=0.475)]，PFS 分别为8.7个月和7.7个月[HR0.927(95%CI 0.65，1.292；P=0.292)]，反应时间分别为7.6个月和6.4个月(P=0.372)。结论：长春瑞滨与同步三维适形放疗联合在治疗局部晚期非小细胞肺癌患者方面具有明显的优势。
目的：觀察長春瑞濱與同步三維適形放療聯閤治療跼部晚期非小細胞肺癌的有效性和安全性。方法：2010年5月-2013年9月收治跼部晚期非小細胞肺癌患者136例，隨機分為試驗組和對照組，各68例，對照組給予長春瑞濱化療，試驗組在長春瑞濱化療的基礎上聯閤三維適形放療。結果：試驗組和對照組的平均隨訪期12.2箇月，OS分彆為17.2箇月和15.7箇月[HR0.975(95%CI 0.655，1.451；P=0.475)]，PFS 分彆為8.7箇月和7.7箇月[HR0.927(95%CI 0.65，1.292；P=0.292)]，反應時間分彆為7.6箇月和6.4箇月(P=0.372)。結論：長春瑞濱與同步三維適形放療聯閤在治療跼部晚期非小細胞肺癌患者方麵具有明顯的優勢。
목적：관찰장춘서빈여동보삼유괄형방료연합치료국부만기비소세포폐암적유효성화안전성。방법：2010년5월-2013년9월수치국부만기비소세포폐암환자136례，수궤분위시험조화대조조，각68례，대조조급여장춘서빈화료，시험조재장춘서빈화료적기출상연합삼유괄형방료。결과：시험조화대조조적평균수방기12.2개월，OS분별위17.2개월화15.7개월[HR0.975(95%CI 0.655，1.451；P=0.475)]，PFS 분별위8.7개월화7.7개월[HR0.927(95%CI 0.65，1.292；P=0.292)]，반응시간분별위7.6개월화6.4개월(P=0.372)。결론：장춘서빈여동보삼유괄형방료연합재치료국부만기비소세포폐암환자방면구유명현적우세。
Objective:To observe the efficacy and safety of navelbine combined with synchronous three dimensional conformal radiotherapy in the treatment of locally advanced non small cell lung cancer.Methods:136 patients with locally advanced non small cell lung cancer were selected from May 2010 to September 2013.They were randomly divided into the experimental group and the control group with 68 cases in each.The control group were given navelbine chemotherapy,and the experimental group were given combined with three dimensional conformal radiotherapy on the basis of navelbine.Results:The average follow-up period of the experimental group and the control group was 12.2 months.OS were respectively 17.2 months and 15.7 months [HR0.975(95% CI 0.655,1.451;P=0.475)];PFS were respectively 8.7 months and 7.7 months[HR0.927(95% CI 0.65,1.292;P=0.292)].The response times were respectively 7.6 months and 6.4 months(P=0.372).Conclusion:Navelbine combined with synchronous three dimensional conformal radiotherapy in the treatment of patients with locally advanced non small cell lung cancer have obvious advantage.
