CAJ | 학술논문

目的：探讨华法林对老年非瓣膜房颤抗栓疗效及安全性。方法：2011年1月-2013年12月收治老年非瓣膜房颤患者80例，分为华法林组与阿司匹林组，对两组患者的抗栓疗效与安全性进行对比与分析。结果：华法林组患者的终点事件发生率5%，阿司匹林组30%，差异具有统计学意义(P＜0.05)。华法林组的出血发生率5%，阿司匹林组5%，差异不具有统计学意义(P＞0.05)。结论：华法林在老年非瓣膜房颤治疗中应用抗栓效果良好，具有很高的安全性，且终点事件发生率较低，值得推广与应用。
목적：탐토화법림대노년비판막방전항전료효급안전성。방법：2011년1월-2013년12월수치노년비판막방전환자80례，분위화법림조여아사필림조，대량조환자적항전료효여안전성진행대비여분석。결과：화법림조환자적종점사건발생솔5%，아사필림조30%，차이구유통계학의의(P＜0.05)。화법림조적출혈발생솔5%，아사필림조5%，차이불구유통계학의의(P＞0.05)。결론：화법림재노년비판막방전치료중응용항전효과량호，구유흔고적안전성，차종점사건발생솔교저，치득추엄여응용。
Objective:To explore the antithrombotic curative effect and safety of warfarin on elderly nonvalvular atrial fibrillation. Methods:80 elderly patients with nonvalvular atrial fibrillation were selected from January 2011 to December 2013.They were divided into the warfarin group and the aspirin group.The antithrombotic curative effect and safety of two groups were compared and analyzed.Results:The endpoint events occurrence rate of patients in the warfarin group was 5%,and that of the aspirin group was 30%;the difference was statistically significant(P<0.05).The bleeding occurrence rate of patients in the warfarin group was 5%,and that of the aspirin group was 5%;the difference was not statistically significant(P>0.05).Conclusion:The application of warfarin in the treatment of elderly nonvalvular atrial fibrillation has good antithrombotic effect,very high security,and lower endpoint events occurrence rate.It is worthy of promotion and application.