中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
3期
121-121,123
,共2页
微柱凝胶%不规则抗体%筛查%输血%溶血现象
微柱凝膠%不規則抗體%篩查%輸血%溶血現象
미주응효%불규칙항체%사사%수혈%용혈현상
Microcolumn agglutination%Irregular antibody%Screening%Blood transfusion%Hemolysis phenomenon
目的：鉴定有妊娠史或输血史的患者血浆中的不规则抗体，避免或降低输血反应中溶血现象的发生。方法：使用coombs IgG微柱凝胶卡筛查和鉴定1145例有妊娠史或输血史患者的血液标本中的不规则抗体，将不规则抗体标本中的阳性标本交叉配血。结果：26例患者不规则抗体阳性，阳性率2.28%。其中抗-D 4例，抗-E 3例，抗-C 1例，抗-A12例，抗-M 3例，抗-EC 2例，抗-Cc 2例，抗-JKa 1例，抗-JKb 2例，抗-FYa 1例，抗-Lea 2例，非特异性抗体3例。结论：筛查不规则抗体可有效避免或减少输血反应中溶血现象的发生，确保安全的进行输血，特别对有妊娠史或输血史的患者具有极其重要的意义。
目的：鑒定有妊娠史或輸血史的患者血漿中的不規則抗體，避免或降低輸血反應中溶血現象的髮生。方法：使用coombs IgG微柱凝膠卡篩查和鑒定1145例有妊娠史或輸血史患者的血液標本中的不規則抗體，將不規則抗體標本中的暘性標本交扠配血。結果：26例患者不規則抗體暘性，暘性率2.28%。其中抗-D 4例，抗-E 3例，抗-C 1例，抗-A12例，抗-M 3例，抗-EC 2例，抗-Cc 2例，抗-JKa 1例，抗-JKb 2例，抗-FYa 1例，抗-Lea 2例，非特異性抗體3例。結論：篩查不規則抗體可有效避免或減少輸血反應中溶血現象的髮生，確保安全的進行輸血，特彆對有妊娠史或輸血史的患者具有極其重要的意義。
목적：감정유임신사혹수혈사적환자혈장중적불규칙항체，피면혹강저수혈반응중용혈현상적발생。방법：사용coombs IgG미주응효잡사사화감정1145례유임신사혹수혈사환자적혈액표본중적불규칙항체，장불규칙항체표본중적양성표본교차배혈。결과：26례환자불규칙항체양성，양성솔2.28%。기중항-D 4례，항-E 3례，항-C 1례，항-A12례，항-M 3례，항-EC 2례，항-Cc 2례，항-JKa 1례，항-JKb 2례，항-FYa 1례，항-Lea 2례，비특이성항체3례。결론：사사불규칙항체가유효피면혹감소수혈반응중용혈현상적발생，학보안전적진행수혈，특별대유임신사혹수혈사적환자구유겁기중요적의의。
Objective:To identify the irregular antibody in the blood plasma of patients with pregnancy history or blood transfusion history,to avoid or reduce hemolysis reaction in blood transfusion.Methods:Using coombs IgG microtube column agglutinatior screened and identified the irregular antibody in the blood plasma of patients with pregnancy history or blood transfusion history. The positive samples in the irregular antibody samples were given cross matching.Results:The irregular antibodies of 26 patients were positive,and the positive rate was 2.28%.Among 4 cases were anti-D,3 cases were anti-E;1 case was anti-C;2 cases were anti-A1;3 cases were anti-M;2 cases were anti-EC;2 cases were anti-Cc;1 case was anti-JKa;2 cases were anti-JKb;1 case was anti-FYa;2 cases were anti-Lea;3 cases were non-specific antibody.Conclusion:Irregular antibodies screening can effectively avoid or reduce the occurrence of hemolysis phenomenon in transfusion reaction,and ensure the safety of blood transfusion.It has the extremely vital significance especially for the patients with pregnancy history or blood transfusion history.
