CAJ | 학술논문

目的：了解该院药品不良反应（ADR）的发生特点，促进临床合理用药。方法对该院2012—2013年上报的581例ADR 报告进行统计和分析。结果581例 ADR 报告中，男性290例，女性291例，基本持平；静脉给药方式引发的 ADR 最多，占总例数的72．81％，抗感染药物引起的 ADR 最多，占总例数的26．68％，其次为中药制剂，占总例数的17．21％；ADR 表现以皮肤及附件损伤最为常见，占总例数的28．92％；ADR 报告分类多为一般，占总数的91．57％。结论临床应重视药品不良反应的报告和监测工作，慎用中药制剂，合理使用抗感染药物，以减少 ADR 的发生。
목적：료해해원약품불량반응（ADR）적발생특점，촉진림상합리용약。방법대해원2012—2013년상보적581례ADR 보고진행통계화분석。결과581례 ADR 보고중，남성290례，녀성291례，기본지평；정맥급약방식인발적 ADR 최다，점총례수적72．81％，항감염약물인기적 ADR 최다，점총례수적26．68％，기차위중약제제，점총례수적17．21％；ADR 표현이피부급부건손상최위상견，점총례수적28．92％；ADR 보고분류다위일반，점총수적91．57％。결론림상응중시약품불량반응적보고화감측공작，신용중약제제，합리사용항감염약물，이감소 ADR 적발생。
Objective To explore the characteristics of the adverse drug reaction (ADR)in The Second People’s Hospital and to pro-mote rational drug use.Methods Five hundred and eighty-one cases of ADR reported in 2012-2013 were statistically analyzed.Re-sults Of 581 cases of ADR reports,there were 290 cases of male,291 cases of female;There were 72.81% of ADR caused by intrave-nous administration,26.68% of ADR caused by anti-infective drugs,followed by 17.21% of ADR caused by Chinese materia medica preparations.The most common manifestation of ADR was damage to skin and annexa,accounting for 28.92%.ADR reports were main-ly classified into the general category,accounting for 91.57%.Conclusions Great attention should be paid to reporting and monitoring of adverse drug reactions in clinic.Care should be taken to the use of Chinese material medica preparations and anti-infective drugs should be rationally used so as to reduce the incidence of ADR.