CAJ | 학술논문

目的：探讨结合皮肤镜观察果酸治疗黄褐斑的临床疗效。方法：对80例黄褐斑患者进行果酸治疗，每3周治疗1次，连续治疗5次，采用Microskin II多功能皮肤镜图像分析系统评价临床疗效。结果：80例患者，总有效率达77.5%。MASI评分从15.82降至治疗后的8.65。患者满意率为82.5%。经过皮肤镜检查，治疗后患者的a值与b值明显降低，而ITA值明显上升，治疗前后对比，差异有统计学意义(＜0.05)，无严重并发症发生且半年随访无1例复发。此外，病程＜1年患者各检测值优于1～5年和＞5年患者，病程＜1年与1～5年和＞5年患者各检测值相比差异有统计学意义（＜0.05），提示黄褐斑病程越短，果酸治疗效果越好。结论：果酸治疗黄褐斑安全、有效，皮肤镜可较客观地评价其疗效。
목적：탐토결합피부경관찰과산치료황갈반적림상료효。방법：대80례황갈반환자진행과산치료，매3주치료1차，련속치료5차，채용Microskin II다공능피부경도상분석계통평개림상료효。결과：80례환자，총유효솔체77.5%。MASI평분종15.82강지치료후적8.65。환자만의솔위82.5%。경과피부경검사，치료후환자적a치여b치명현강저，이ITA치명현상승，치료전후대비，차이유통계학의의(＜0.05)，무엄중병발증발생차반년수방무1례복발。차외，병정＜1년환자각검측치우우1～5년화＞5년환자，병정＜1년여1～5년화＞5년환자각검측치상비차이유통계학의의（＜0.05），제시황갈반병정월단，과산치료효과월호。결론：과산치료황갈반안전、유효，피부경가교객관지평개기료효。
Objective To observe and evaluate the clinical efficacy of tartaric acid on chloasma by dermoscope. Methods 80 patients with chloasma were treated by tartaric acid continuous treatment for 5 times at an interval of 3 weeks and the Microskin II multi- functional dermatoscope image analysis system was used to evaluate the clinical therapeutic effect. Results The total effective rate of 80 patients was 77.5%.the MASI score decreased from 15.82 to 8.65.The satisfactory rate was 82.5% .With the dermatoscope examination, both a and b values were significantly decreased and the value of ITA was significantly increased.The differences were statistically significant before and after treatment ( <0.05).No serious complications occurred and no case recurred after half a year follow- up.In addition, the course of <1 years in patients with various values than patients with 1- 5 and>5 years, the course of<1 years compared with patients with 1- 5 and>5 years,the difference was statistically significant ( <0.05),suggesting that tartaric acid for the treatment of chloasma, with the course shorter,the treatment effect is better. Conclusion Our study findings indicate that tartaric acid is safe and effective in the treatment of chloasma,dermoscopy is an objective tool to evaluate the clinical effect.