中国执业药师
中國執業藥師
중국집업약사
CHINA LICENSED PHARMACIST
2015年
1期
3-7
,共5页
陈翔%谢结英%陈如大%邓冲%李鹏翀
陳翔%謝結英%陳如大%鄧遲%李鵬翀
진상%사결영%진여대%산충%리붕충
抗菌药物专项整治方案%肿瘤科%抗菌药物合理用药
抗菌藥物專項整治方案%腫瘤科%抗菌藥物閤理用藥
항균약물전항정치방안%종류과%항균약물합리용약
Special Regulation Scheme Against Antibacterial Agents%Oncology Department%Antibacterial A-gents Rational Drug Use
目的：调查抗菌药物专项整治方案实施前后我院肿瘤科应用抗菌药物的情况，评价其应用的合理性，分析专项整治后我院肿瘤科抗菌药物应用的改善情况。方法：选择南海区人民医院肿瘤科2010年10-11月与2011年10-11月肿瘤科病历821例，对抗菌药物的用药种类、用药频度、联合用药、用药合理性等进行调查。结果：专项整治前后，我院肿瘤科抗菌药物应用种类以广谱抗菌药为主，用药种类变化差异无显著性，主要类属于第3、4代头孢类及氟喹诺酮类药物。抗菌药物以单用为主，专项整治前后抗菌药物的联用情况差异无显著性。在进行抗菌药物的合理性评价时发现，感染治疗组在专项整治前后合理性差异不显著；预防用药组抗菌药物专项整治后不合理用药的数目较专项整治前降低，结果有统计学意义（P =0.028）。结论：抗菌药物临床应用专项整治活动方案的大范围推广，使我院肿瘤科抗菌药物使用情况得到部分改善，但在累计使用强度及病原学检测等方面仍有待改进。
目的：調查抗菌藥物專項整治方案實施前後我院腫瘤科應用抗菌藥物的情況，評價其應用的閤理性，分析專項整治後我院腫瘤科抗菌藥物應用的改善情況。方法：選擇南海區人民醫院腫瘤科2010年10-11月與2011年10-11月腫瘤科病歷821例，對抗菌藥物的用藥種類、用藥頻度、聯閤用藥、用藥閤理性等進行調查。結果：專項整治前後，我院腫瘤科抗菌藥物應用種類以廣譜抗菌藥為主，用藥種類變化差異無顯著性，主要類屬于第3、4代頭孢類及氟喹諾酮類藥物。抗菌藥物以單用為主，專項整治前後抗菌藥物的聯用情況差異無顯著性。在進行抗菌藥物的閤理性評價時髮現，感染治療組在專項整治前後閤理性差異不顯著；預防用藥組抗菌藥物專項整治後不閤理用藥的數目較專項整治前降低，結果有統計學意義（P =0.028）。結論：抗菌藥物臨床應用專項整治活動方案的大範圍推廣，使我院腫瘤科抗菌藥物使用情況得到部分改善，但在纍計使用彊度及病原學檢測等方麵仍有待改進。
목적：조사항균약물전항정치방안실시전후아원종류과응용항균약물적정황，평개기응용적합이성，분석전항정치후아원종류과항균약물응용적개선정황。방법：선택남해구인민의원종류과2010년10-11월여2011년10-11월종류과병력821례，대항균약물적용약충류、용약빈도、연합용약、용약합이성등진행조사。결과：전항정치전후，아원종류과항균약물응용충류이엄보항균약위주，용약충류변화차이무현저성，주요류속우제3、4대두포류급불규낙동류약물。항균약물이단용위주，전항정치전후항균약물적련용정황차이무현저성。재진행항균약물적합이성평개시발현，감염치료조재전항정치전후합이성차이불현저；예방용약조항균약물전항정치후불합리용약적수목교전항정치전강저，결과유통계학의의（P =0.028）。결론：항균약물림상응용전항정치활동방안적대범위추엄，사아원종류과항균약물사용정황득도부분개선，단재루계사용강도급병원학검측등방면잉유대개진。
Objective: To investigate the application of antibacterial agents in oncology department of our hospi-tal before and after performing the special regulation of antibacterial agents , evaluate the rational medication and the improvement of application of antibacterial agents after implementing the special regulation . Methods: An in-vestigation was conducted on the varieties and use frequency of antibacterial agents , combination of drug use and medication rationality among 821 cancer patients chosen from the oncology department of the People ’ s Hospital of Nanhai Disctrict from October to November of 2010 and October to November of 2011 . Results: Before and after the implementation of special regulation of antibacterial drugs , the antibacterial drugs with broad-spectrum were mainly used and there was no big changes of the drug varieties which mainly belonged to the third or the fourth generations of cephalosporins and fluoroquinolones . The antibacterial agents were mainly used singly . Before and af-ter the implementation of renovation scheme of antibacterial agents , there was no significant difference in the com-bined use of antibacterial agents and in the evaluation of the rational drug use , there was no significant difference in the infection-treatment groups . After the special regulation was applied , the number of unreasonable drug applica-tion in preventive-medication group decreased and the results had statistical significance ( P = 0 . 028 ) . Conclusion:Due to the big range promotion of special regulation of antibacterial agents in clinical practice , some improvement was made in the reasonable use of antibacterial agents , but the accumulation of use intensity and the etiological examination should be further improved .
