医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
26期
102-103
,共2页
肾病综合征%股骨头坏死%糖皮质激素
腎病綜閤徵%股骨頭壞死%糖皮質激素
신병종합정%고골두배사%당피질격소
nephrotic syndrome%Femoral head necrosis%glucocorticoids
目的：探讨肾病综合征并发股骨头坏死的相关危险因素及诊治体会。方法：对我院肾病综合征并发股骨头坏死的10例患者的临床资料进行回顾性分析，并与同期间50例肾病综合征无股骨头坏死组患者的年龄、血浆白蛋白、24小时尿蛋白定量、总胆固醇、甘油三酯、纤维蛋白原及激素用量等指标进行比较。结果：股骨头坏死组在应用糖皮质激素剂量、CHOL、TG、FIB上与股骨头无坏死组相比有显著性差异（P＜0.05）。结论：大剂量糖皮质激素应用在股骨头坏死中有重要作用，避免大剂量糖皮质激素盲目应用及积极控制高脂血症是预防股骨头坏死的有效方法。
目的：探討腎病綜閤徵併髮股骨頭壞死的相關危險因素及診治體會。方法：對我院腎病綜閤徵併髮股骨頭壞死的10例患者的臨床資料進行迴顧性分析，併與同期間50例腎病綜閤徵無股骨頭壞死組患者的年齡、血漿白蛋白、24小時尿蛋白定量、總膽固醇、甘油三酯、纖維蛋白原及激素用量等指標進行比較。結果：股骨頭壞死組在應用糖皮質激素劑量、CHOL、TG、FIB上與股骨頭無壞死組相比有顯著性差異（P＜0.05）。結論：大劑量糖皮質激素應用在股骨頭壞死中有重要作用，避免大劑量糖皮質激素盲目應用及積極控製高脂血癥是預防股骨頭壞死的有效方法。
목적：탐토신병종합정병발고골두배사적상관위험인소급진치체회。방법：대아원신병종합정병발고골두배사적10례환자적림상자료진행회고성분석，병여동기간50례신병종합정무고골두배사조환자적년령、혈장백단백、24소시뇨단백정량、총담고순、감유삼지、섬유단백원급격소용량등지표진행비교。결과：고골두배사조재응용당피질격소제량、CHOL、TG、FIB상여고골두무배사조상비유현저성차이（P＜0.05）。결론：대제량당피질격소응용재고골두배사중유중요작용，피면대제량당피질격소맹목응용급적겁공제고지혈증시예방고골두배사적유효방법。
Objective: to study the nephrotic syndrome complicated by the experience of diagnosis and treatment of risk factors and related to femoral head necrosis. Methods: a total of nephrotic syndrome complicated with femoral head necrosis, the clinical data of 10 patients were retrospectively analyzed and compared with the same period of 50 cases of nephrotic syndrome patients with femoral head necrosis group age, serum albumin, 24 hours urinary protein quantitative, total cholesterol, triglyceride, fibrinogen and dosage of hormones and other indicators. Results: femoral head necrosis group in the application of glucocorticoids dose, CHOL, TG, FIB compared with no necrosis of femoral head group with significant difference (P < 0.05). Conclusion: high-dose glucocorticoids application play an important role in the femoral head necrosis, avoid blind application of high-dose glucocorticoids and active control hyperlipidemia is one of the effective methods to prevent femoral head necrosis.
