CAJ | 학술논문

目的：探讨红景天功能饮料对小鼠抗疲劳和耐缺氧能力的影响。方法分别以160、80、40 ml／kg剂量的红景天功能饮料给小鼠连续灌胃30 d ，通过负重游泳试验及检测血尿素、肝糖原和血乳酸水平评价各组小鼠的抗疲劳功能；通过常压耐缺氧实验、亚硝酸钠中毒实验和急性脑缺血（断头）实验评价各组小鼠耐缺氧功能。结果与给予纯水灌胃的对照组相比，高、中剂量组小鼠负重游泳时间明显延长（P＜0．05）；高剂量组小鼠的血清尿素含量显著降低（P＜0．05），肝糖原含量增高（P＜0．05）；3个剂量组小鼠的血乳酸曲线下面积均减小（P＜0．05）；高、中剂量组小鼠的缺氧死亡时间、中毒后存活时间明显延长（P＜0．05）；高剂量组小鼠的断头后张口喘气时间明显延长（P＜0．01）。结论红景天功能饮料可以提高小鼠的抗疲劳能力和耐缺氧能力。
목적：탐토홍경천공능음료대소서항피로화내결양능력적영향。방법분별이160、80、40 ml／kg제량적홍경천공능음료급소서련속관위30 d ，통과부중유영시험급검측혈뇨소、간당원화혈유산수평평개각조소서적항피로공능；통과상압내결양실험、아초산납중독실험화급성뇌결혈（단두）실험평개각조소서내결양공능。결과여급여순수관위적대조조상비，고、중제량조소서부중유영시간명현연장（P＜0．05）；고제량조소서적혈청뇨소함량현저강저（P＜0．05），간당원함량증고（P＜0．05）；3개제량조소서적혈유산곡선하면적균감소（P＜0．05）；고、중제량조소서적결양사망시간、중독후존활시간명현연장（P＜0．05）；고제량조소서적단두후장구천기시간명현연장（P＜0．01）。결론홍경천공능음료가이제고소서적항피로능력화내결양능력。
Objective To study the effect of functional beverages of rhodiola on the ability of anti-fatigue and anoxia endurance in mice .Methods Functional beverages of rhodiola was consecutively orally given to mice with the doses of 160,80 and 40 ml/kg for 30 days respectively.Test of burdened swimming ,and urea,hepatic glycogen and lactic acid determination were used to assess the function of anti-fatigue of mice .Tests of anoxia endurance under normal pressure ,sodium nitrite poisoning and acute cerebral ischemia ( decapitation ) were used to assess the function of anoxia endurance of mice .Results Compared with control group ,the mice in the high and middle dose groups showed a longer burdened swimming time(P<0.05);The serum urea content of mice decreased significantly (P<0.05),but the hepatic glycogen content increased in the high dose group (P<0.05).The area under curve of blood lactic acid all decreased in the three dose groups ( P<0 .05 ) .The mice in the high and middle dose groups showed a longer survival time under anoxia condition and a longer survival time after being poisoned by sodium nitrite ( P<0 .05 ) .The mice in the high dose group showed a longer breathing time after decapitation (P<0.01).Conclusion Functional beverages of rhodiola can contribute to imporve the function of anti-fatigue and anoxia endurance in mice .