广西医学
廣西醫學
엄서의학
GUANGXI MEDICAL JOURNAL
2014年
12期
1747-1750
,共4页
膀胱癌%经尿道膀胱肿瘤电切术%肿瘤残留%多因素分析
膀胱癌%經尿道膀胱腫瘤電切術%腫瘤殘留%多因素分析
방광암%경뇨도방광종류전절술%종류잔류%다인소분석
Bladder cancer%Transurethral resection of bladder tumor%Residual tumor%Multivariate analysis
目的：探讨初次经尿道膀胱肿瘤电切术（ TURBt）术后肿瘤残留的相关影响因素，为临床诊治提供参考。方法回顾性分析98例非肌层浸润膀胱癌（ NMIBC ）实施TURBt术并于术后2～6周内行re-TURBt或开放手术膀胱癌患者的临床病理资料，采用χ2检验及多因素logistic回归分析相关临床病理因素与肿瘤残留的关系。结果初次TURBt术后39例Ta期肿瘤残留6例（15．38％），49例T1期肿瘤残留19例（38．78％）。相关分析显示肿瘤数目、组织病理类型、电切设备与肿瘤残留无关（P＞0．05），而肿瘤大小、位置、生长方式、分级、分期、电切方法、术者经验与肿瘤残留相关（ P＜0．05）。 logistic多因素回归分析得出肿瘤分级、分期、生长方式为主要相关因素。结论影响初次TURBt术后肿瘤残留的相关因素有肿瘤大小、肿瘤位置、生长方式、分级、分期、电切方法、术者经验等。
目的：探討初次經尿道膀胱腫瘤電切術（ TURBt）術後腫瘤殘留的相關影響因素，為臨床診治提供參攷。方法迴顧性分析98例非肌層浸潤膀胱癌（ NMIBC ）實施TURBt術併于術後2～6週內行re-TURBt或開放手術膀胱癌患者的臨床病理資料，採用χ2檢驗及多因素logistic迴歸分析相關臨床病理因素與腫瘤殘留的關繫。結果初次TURBt術後39例Ta期腫瘤殘留6例（15．38％），49例T1期腫瘤殘留19例（38．78％）。相關分析顯示腫瘤數目、組織病理類型、電切設備與腫瘤殘留無關（P＞0．05），而腫瘤大小、位置、生長方式、分級、分期、電切方法、術者經驗與腫瘤殘留相關（ P＜0．05）。 logistic多因素迴歸分析得齣腫瘤分級、分期、生長方式為主要相關因素。結論影響初次TURBt術後腫瘤殘留的相關因素有腫瘤大小、腫瘤位置、生長方式、分級、分期、電切方法、術者經驗等。
목적：탐토초차경뇨도방광종류전절술（ TURBt）술후종류잔류적상관영향인소，위림상진치제공삼고。방법회고성분석98례비기층침윤방광암（ NMIBC ）실시TURBt술병우술후2～6주내행re-TURBt혹개방수술방광암환자적림상병리자료，채용χ2검험급다인소logistic회귀분석상관림상병리인소여종류잔류적관계。결과초차TURBt술후39례Ta기종류잔류6례（15．38％），49례T1기종류잔류19례（38．78％）。상관분석현시종류수목、조직병리류형、전절설비여종류잔류무관（P＞0．05），이종류대소、위치、생장방식、분급、분기、전절방법、술자경험여종류잔류상관（ P＜0．05）。 logistic다인소회귀분석득출종류분급、분기、생장방식위주요상관인소。결론영향초차TURBt술후종류잔류적상관인소유종류대소、종류위치、생장방식、분급、분기、전절방법、술자경험등。
Objective To investigate the related influencing facors for residual tumor after first transurethral resection of bladder tumor(TURBt),and to provide references for the clinical diagnosis and treatment .Methods A retrospective analysis was performed in the 98 patients with non-muscle invasive bladder cancer ( NMIBC ) after first TURBt,and the patients accepted re-TURBt or open surgery 2 to 6 weeks after first TURBt .The association between residual tumor and clinicopathologic variables was evaluated by Chi-sguare test and multivariate logistic regression analysis.Results After first TURBt,residual tumor was present in 6 of 39(15.38%) patients with Ta bladder cancer and in 19 of 49(38.78%) patients with T1 bladder cancer.Chi-sguare test suggested that the number of tumor ,pathological type of tumor and transurethral device were not associated with residual tumor (P>0.05),but the tumor size,position of tumor,growing pattern of tumor,tumor grade,tumor stage,method of transurethral resection and the operator′s experience were associated with residual tumor ( P<0.05).The results of multivariate logistic regression analysis showed that tumor grade ,tumor stage and the growing pattern of tumor were the major related factors .Conclusion The related influencing factors for residual tumor of bladder cancer include tumor size ,position of tumor ,growing pattern of tumor ,tumor grade , tumor stage ,method of transurethral resection and the operator′s experience .
