CAJ | 학술논문

目的：探讨尿道狭窄术后应用康复新液灌注治疗的临床疗效。方法按照随机数表法将本院收治的80例行尿道狭窄手术治疗的患者随机分为对照组与观察组。每组各40例。对照组患者予以常规治疗，观察组患者在常规治疗基础上加用康复新液灌注。对比两组患者临床治疗效果及术后尿道再狭窄发生情况。结果治疗前，两组患者国际前列腺症状评分（IPSS）、生活质量（QOL）评分、最大尿流率（Qmax）、尿道内径及残余尿（PVR）比较未见显著差异（P＞0.05）；治疗后1个月，两组患者上述指标均较治疗前显著改善（P＜0.05），且观察组改善更为明显；治疗后3个月，观察组患者发生尿道再狭窄5例（12.5%），显著低于对照组[13例（32.5%）]（χ2＝4.5878，P＝0.0320）。观察组尿道再狭窄患者的尿道狭窄长度低于对照组，尿道内径高于对照组，差异均有显著性（P＜0.05）。结论尿道狭窄术后应用康复新液灌注治疗可显著提高手术的治疗效果，且再狭窄发生率低，值得临床推广应用。
목적：탐토뇨도협착술후응용강복신액관주치료적림상료효。방법안조수궤수표법장본원수치적80례행뇨도협착수술치료적환자수궤분위대조조여관찰조。매조각40례。대조조환자여이상규치료，관찰조환자재상규치료기출상가용강복신액관주。대비량조환자림상치료효과급술후뇨도재협착발생정황。결과치료전，량조환자국제전렬선증상평분（IPSS）、생활질량（QOL）평분、최대뇨류솔（Qmax）、뇨도내경급잔여뇨（PVR）비교미견현저차이（P＞0.05）；치료후1개월，량조환자상술지표균교치료전현저개선（P＜0.05），차관찰조개선경위명현；치료후3개월，관찰조환자발생뇨도재협착5례（12.5%），현저저우대조조[13례（32.5%）]（χ2＝4.5878，P＝0.0320）。관찰조뇨도재협착환자적뇨도협착장도저우대조조，뇨도내경고우대조조，차이균유현저성（P＜0.05）。결론뇨도협착술후응용강복신액관주치료가현저제고수술적치료효과，차재협착발생솔저，치득림상추엄응용。
Objective To investigate the clinical efifcacy of postoperative urethral stricture used Kangfuxin perfusion therapy. Method 80 patients with urethral stricture routine surgery were randomly divided into two groups according to the random number table, 40 patients in each group. Control group received conventional treatment, observation group on the basis of conventional treatment plus Kangfuxin perfusion therapy. Compared two groups with clinically therapeutic effect and the occurrence of postoperative urethral restenosis. Result Before treatment, IPSS, QOL, urethral diameter, Qmax and PVR had no signiifcant difference between two groups (P>0.05), 1 month after treatment, all indicators above of patients signiifcantly improved (P<0.05), observation group had more obvious effect (P<0.05). 3 months after treatment, urethral restenosis in control group was 32.50%, and observation group was 12.50%, patients in observation group of urethral overall incidence of restenosis was signiifcantly lower than control group. The urethral restenosis with urethral stricture length and diameter of the urethra of observation group were better than control group (P<0.05). Conclusion Postoperative urethral stricture used Kangfuxin perfusion therapy can signiifcantly improve the treatment of urethral stricture surgery, and has a low incidence of restenosis, it is worthy of clinical application.