CAJ | 학술논문

目的：研究帕瑞昔布钠联合臂丛麻醉对断肢（指）术后镇痛的临床疗效。方法：选择择期进行上肢断肢（指）再植手术的患者60例，按照双盲法随机分为两组：超前镇痛组（30例）为麻醉成功后立即给予帕瑞昔布钠40mg（生理盐水稀释2mL）；对照组（30例）给予安慰剂生理盐水2mL作对照，观察两组患者术后PCIA的芬太尼用量、MAP、HR、疼痛（ NRS）评分及不良反应发生率。结果：超前镇痛组的芬太尼用量明显低于对照组，镇痛有效率较对照组高，且不良反应发生率显著低于对照组。结论：瑞昔布钠联合臂丛麻醉对断肢（指）术后镇痛在效果和安全性上均有明显的优势。
목적：연구파서석포납연합비총마취대단지（지）술후진통적림상료효。방법：선택택기진행상지단지（지）재식수술적환자60례，안조쌍맹법수궤분위량조：초전진통조（30례）위마취성공후립즉급여파서석포납40mg（생리염수희석2mL）；대조조（30례）급여안위제생리염수2mL작대조，관찰량조환자술후PCIA적분태니용량、MAP、HR、동통（ NRS）평분급불량반응발생솔。결과：초전진통조적분태니용량명현저우대조조，진통유효솔교대조조고，차불량반응발생솔현저저우대조조。결론：서석포납연합비총마취대단지（지）술후진통재효과화안전성상균유명현적우세。
Objective:To investigate the clinical efficacy of parecoxib sodium combined with brachial plexus anesthesia on postoper -ative analgesia after replantation of severed limb (finger).Methods:60 cases of patients received upper limb (finger) replantation sur-gery were selected and randomly divided into two groups:preemptive analgesia group (30 cases) were given 40 mg parecoxib sodium immediately after success anesthesia;control group (30 cases) received 2mL saline as placebo .We observed the fentanyl consumption , MAP, HR, pain ( NRS) score and the incidence of adverse reaction in three groups of patients after surgery.Results:The fentanyl con-sumption in preemptive analgesia was significantly lower than control group , the analgesic efficiency were significantly higher than con-trol group, while the incidence of adverse reactions was significantly lower than control group.Conclusion:The parecoxib sodium com-bined with brachial plexus anesthesia on limb (finger) postoperative analgesia has obvious advantages in efficacy and safety.