CAJ | 학술논문

目的：探讨使用人血丙种球蛋白(IVIG)联合甲基强的松龙治疗对川崎病预后的影响。方法对56例川崎病患儿，采用静脉注射丙种球蛋白、阿司匹林治疗及丙种球蛋白、阿司匹林联合甲基波尼松龙治疗。第1组每日丙种球蛋白用1g/kg，连用2d；第2组丙种球蛋白1g/kg加甲基波尼松龙30mg/kg连用2d，比较两组治疗后急性期临床症状消失时间和预防冠状动脉损害(CAL)发生率。结果两组在急性期症状消失时间和冠状动脉损害发生方面有显著差异。结论在联合使用甲基波尼松龙及阿司匹林片治疗可有效缓解临床症状，减少冠状动脉病变（GAL）发生率，值得推广。
목적：탐토사용인혈병충구단백(IVIG)연합갑기강적송룡치료대천기병예후적영향。방법대56례천기병환인，채용정맥주사병충구단백、아사필림치료급병충구단백、아사필림연합갑기파니송룡치료。제1조매일병충구단백용1g/kg，련용2d；제2조병충구단백1g/kg가갑기파니송룡30mg/kg련용2d，비교량조치료후급성기림상증상소실시간화예방관상동맥손해(CAL)발생솔。결과량조재급성기증상소실시간화관상동맥손해발생방면유현저차이。결론재연합사용갑기파니송룡급아사필림편치료가유효완해림상증상，감소관상동맥병변（GAL）발생솔，치득추엄。
Objective Explores the use of human serum gamma globulin (IVIG) combined with methyl-prednisolone therapy on prognosis of Kawasaki disease. Methods 56 cases of children with Kawasaki disease using intravenous gamma globulin and aspirin therapy and intravenous immunoglobulin treatment, aspirin and methyl bonisonglong. 1th set of daily intravenous immunoglobulin 1g/kg, using 2D;2nd group gamma globulin used methyl bonisonglong 30mg/kg 1g/kg plus 2D, comparing acute clinical symptoms disappeared after treatment and prevention of coronary artery damage (CAL) incidence. Results Two sets of symptoms in the acute phase and significant differences of the coronary artery damage. Conclusion Joint use of methyl bonisonglong and aspirin can effectively relieve symptoms and reduce coronary artery disease (GAL) incidence, it is worth promoting.