影像诊断与介入放射学
影像診斷與介入放射學
영상진단여개입방사학
JOURNAL OF DIAGNOSTIC IMAGING AND INTERVENTIONAL RADIOLOGY
2014年
6期
511-515
,共5页
李延芳%徐辉雄%张一峰%徐军妹%伯小皖%李丹丹%雷凯荣%房林%曲伸
李延芳%徐輝雄%張一峰%徐軍妹%伯小皖%李丹丹%雷凱榮%房林%麯伸
리연방%서휘웅%장일봉%서군매%백소환%리단단%뢰개영%방림%곡신
超声检查%甲状腺结节%甲状腺疾病%声触诊组织量化成像%剪切波弹性成像
超聲檢查%甲狀腺結節%甲狀腺疾病%聲觸診組織量化成像%剪切波彈性成像
초성검사%갑상선결절%갑상선질병%성촉진조직양화성상%전절파탄성성상
Ultrasonography%Thyroid nodules%Thyroid disease%Virtual touch tissue quantification%Shear wave elastography
目的探讨声触诊组织量化成像（VTIQ）剪切波弹性成像技术对不同大小的甲状腺实性结节良恶性鉴别的诊断价值。方法回顾性分析经手术后病理证实的50例患者62个甲状腺实性病灶的常规超声与VTIQ图像资料。先行常规超声检查，对二维超声图像特征进行描述。然后根据病灶大小（≤10 mm和＞10 mm）分为两组，测量良恶性病灶及周边组织在VTIQ上的剪切波速度（SWV），绘制受试者操作特性（ROC）曲线，曲线下面积（AUC）进行组间比较，分析评估VTIQ鉴别甲状腺实性病灶良恶性的诊断价值。结果62个甲状腺病灶中，恶性病灶32个，良性病灶30个。良性病灶与其周边组织的SWV差异无统计学意义（P=0.355）,恶性病灶SWV明显高于其周边组织SWV值（P=0.000）；良恶性病灶周边组织的SWV差异无统计学意义（P=0.164）。≤10 mm的病灶AUC为0.951，鉴别良恶性SWV截断值为2.53 m/s时，准确性85.7%，灵敏度91.3%，特异度75.0%，阳性预测值87.5%，阴性预测值81.8%，优势比31.5。＞10 mm的病灶AUC为0.784，鉴别良恶性SWV截断值为2.56 m/s时，准确性77.8%，灵敏度88.9%，特异度77.2%，阳性预测值61.5%，阴性预测值92.8%，优势比20.8。结论 VTIQ对鉴别甲状腺实性良恶性病灶有一定诊断价值，尤其是对≤10 mm的病灶。
目的探討聲觸診組織量化成像（VTIQ）剪切波彈性成像技術對不同大小的甲狀腺實性結節良噁性鑒彆的診斷價值。方法迴顧性分析經手術後病理證實的50例患者62箇甲狀腺實性病竈的常規超聲與VTIQ圖像資料。先行常規超聲檢查，對二維超聲圖像特徵進行描述。然後根據病竈大小（≤10 mm和＞10 mm）分為兩組，測量良噁性病竈及週邊組織在VTIQ上的剪切波速度（SWV），繪製受試者操作特性（ROC）麯線，麯線下麵積（AUC）進行組間比較，分析評估VTIQ鑒彆甲狀腺實性病竈良噁性的診斷價值。結果62箇甲狀腺病竈中，噁性病竈32箇，良性病竈30箇。良性病竈與其週邊組織的SWV差異無統計學意義（P=0.355）,噁性病竈SWV明顯高于其週邊組織SWV值（P=0.000）；良噁性病竈週邊組織的SWV差異無統計學意義（P=0.164）。≤10 mm的病竈AUC為0.951，鑒彆良噁性SWV截斷值為2.53 m/s時，準確性85.7%，靈敏度91.3%，特異度75.0%，暘性預測值87.5%，陰性預測值81.8%，優勢比31.5。＞10 mm的病竈AUC為0.784，鑒彆良噁性SWV截斷值為2.56 m/s時，準確性77.8%，靈敏度88.9%，特異度77.2%，暘性預測值61.5%，陰性預測值92.8%，優勢比20.8。結論 VTIQ對鑒彆甲狀腺實性良噁性病竈有一定診斷價值，尤其是對≤10 mm的病竈。
목적탐토성촉진조직양화성상（VTIQ）전절파탄성성상기술대불동대소적갑상선실성결절량악성감별적진단개치。방법회고성분석경수술후병리증실적50례환자62개갑상선실성병조적상규초성여VTIQ도상자료。선행상규초성검사，대이유초성도상특정진행묘술。연후근거병조대소（≤10 mm화＞10 mm）분위량조，측량량악성병조급주변조직재VTIQ상적전절파속도（SWV），회제수시자조작특성（ROC）곡선，곡선하면적（AUC）진행조간비교，분석평고VTIQ감별갑상선실성병조량악성적진단개치。결과62개갑상선병조중，악성병조32개，량성병조30개。량성병조여기주변조직적SWV차이무통계학의의（P=0.355）,악성병조SWV명현고우기주변조직SWV치（P=0.000）；량악성병조주변조직적SWV차이무통계학의의（P=0.164）。≤10 mm적병조AUC위0.951，감별량악성SWV절단치위2.53 m/s시，준학성85.7%，령민도91.3%，특이도75.0%，양성예측치87.5%，음성예측치81.8%，우세비31.5。＞10 mm적병조AUC위0.784，감별량악성SWV절단치위2.56 m/s시，준학성77.8%，령민도88.9%，특이도77.2%，양성예측치61.5%，음성예측치92.8%，우세비20.8。결론 VTIQ대감별갑상선실성량악성병조유일정진단개치，우기시대≤10 mm적병조。
Objective To evaluate virtual touch tissue quantification(VTTQ)for differentiating benign and malignant thyroid nodules.Methods 50 patients with 62 pathologically proven benign(30)and malignant(32)thyroid nodules underwent conventional ultrasound and VTIQ examinations.The nodules were divided into two groups of≤10 mm and>10 mm.Shear wave velocities(SWVs) of benign and malignant nodules and surrounding tissues were measured.The receiver operating characteristic curve(ROC)was used to assess the value of VTIQ in differentiating benign and malignant nodules.Areas under the curve(AUC)were compared between the two groups.Results The SWVs between benign nodules and surrounding tissues,between surrounding tissue of benign and malignant nodules were not significantly different(P=0.355,0.164)whereas the SWVs of malignant nodules were significantly higher than that of surrounding tissues(P=0).The AUC were 0.951 for nodules≤10 mm and 0.784 for nodules>10 mm.At SWV cut-off values of 2.53 m/s for nodules≤10 mm and 2.56 m/s for nodules>10 mm,the accuracy was 85.7%and 77.8%,sensitivity was 91.3%and 88.9%, specificity was 75.0%and 77.2%,positive predictive value was 87.5%and 61.5%,negative predictive value was 81.8%and 92.8%, odds ratio was 31.5 and 20.8,respectively.Conclusion VTIQ is valuable in differentiating benign from malignant thyroid nodules.
