湖南师范大学学报(医学版)
湖南師範大學學報(醫學版)
호남사범대학학보(의학판)
JOURNAL OF HUNAN NORMAL UNIVERSITY(MEDICAL SCIENCE)
2014年
4期
83-85
,共3页
孟宪琴%刘伟%屈晓冰%杜万红%刘颖
孟憲琴%劉偉%屈曉冰%杜萬紅%劉穎
맹헌금%류위%굴효빙%두만홍%류영
糖代谢因素%良性前列腺增生症临床进展性
糖代謝因素%良性前列腺增生癥臨床進展性
당대사인소%량성전렬선증생증림상진전성
metabolic factor of glucose%clinical progession of benign prostatic hyperplasia
目的:探讨糖代谢因素对老年人良性前列腺增生症( BPH)临床进展的影响。方法:117例老年BPH患者将年龄≥62岁、PSA≥1.6 ng/mL、PV≥31 mL分为高进展性组(60人),其余为低进展性组(57人),分析比较两组间空腹血糖(FBS)、餐后2小时血糖(2hPBG)、糖化血红蛋白(HbA1c)、空腹胰岛素(FINS)、胰岛素抵抗指数( HOMA-IR)等代谢性因素及BPH患者PV、血清前列腺特异性抗原( PSA)、国际前列腺症状评分( IPSS)、下尿路症状( LUTS)出现时间;用Logistic回归分析BPH临床进展性的危险因素。结果:BPH高进展性组与BPH低进展性组的FBS、2 hPBG、HbA1 c、FINS相比有差异;且BPH高进展性组患者的PV明显大于BPH低进展性组患者,PSA值升高、IPSS分值增加;用Logistic逐步回归分析方法筛查BPH进展性危险因素,显示FBS、FINS为BPH患者临床进展的危险因素。结论:FBS、FINS可促使老年BPH患者的临床进展。
目的:探討糖代謝因素對老年人良性前列腺增生癥( BPH)臨床進展的影響。方法:117例老年BPH患者將年齡≥62歲、PSA≥1.6 ng/mL、PV≥31 mL分為高進展性組(60人),其餘為低進展性組(57人),分析比較兩組間空腹血糖(FBS)、餐後2小時血糖(2hPBG)、糖化血紅蛋白(HbA1c)、空腹胰島素(FINS)、胰島素牴抗指數( HOMA-IR)等代謝性因素及BPH患者PV、血清前列腺特異性抗原( PSA)、國際前列腺癥狀評分( IPSS)、下尿路癥狀( LUTS)齣現時間;用Logistic迴歸分析BPH臨床進展性的危險因素。結果:BPH高進展性組與BPH低進展性組的FBS、2 hPBG、HbA1 c、FINS相比有差異;且BPH高進展性組患者的PV明顯大于BPH低進展性組患者,PSA值升高、IPSS分值增加;用Logistic逐步迴歸分析方法篩查BPH進展性危險因素,顯示FBS、FINS為BPH患者臨床進展的危險因素。結論:FBS、FINS可促使老年BPH患者的臨床進展。
목적:탐토당대사인소대노년인량성전렬선증생증( BPH)림상진전적영향。방법:117례노년BPH환자장년령≥62세、PSA≥1.6 ng/mL、PV≥31 mL분위고진전성조(60인),기여위저진전성조(57인),분석비교량조간공복혈당(FBS)、찬후2소시혈당(2hPBG)、당화혈홍단백(HbA1c)、공복이도소(FINS)、이도소저항지수( HOMA-IR)등대사성인소급BPH환자PV、혈청전렬선특이성항원( PSA)、국제전렬선증상평분( IPSS)、하뇨로증상( LUTS)출현시간;용Logistic회귀분석BPH림상진전성적위험인소。결과:BPH고진전성조여BPH저진전성조적FBS、2 hPBG、HbA1 c、FINS상비유차이;차BPH고진전성조환자적PV명현대우BPH저진전성조환자,PSA치승고、IPSS분치증가;용Logistic축보회귀분석방법사사BPH진전성위험인소,현시FBS、FINS위BPH환자림상진전적위험인소。결론:FBS、FINS가촉사노년BPH환자적림상진전。
Objective To investigate the affect of glucose metabolism in clinical progession of elderly benign prostatichyperplasia(BPH).Methods 117casesofBPHpatientsagedover62years,PSAover1.6ng/mL,PV over 31 mL named high progressive group ( 60 people ) , and the remained named low-progressive group ( 57 peo-ple ) the two groups were analyzed and compared , between fasting blood glucose ( FBS) , 2-hour postprandial glu-cose (2hPBG), glycated hemoglobin (HbA1c), fasting insulin (FINS), insulin resistance index (HOMA-IR) and other metabolic factors and BPH patients PV , serum prostate-specific antigen ( PSA), International Prostate Symptom Score ( IPSS) , lower urinary tract symptoms ( LUTS) appear time;Logistic regression analysis of clinical progression of BPH risk factors .Results There are significant differences between the two groups on FBS、2hPBG、HbA1 c、FINS;the PV on high progressive group was significantly greater than the low , PSA increased , IPSS scores increased;Logistic regression analysis screening the risk factors for BPH progress which display FBS , FINS both are the risk factors to BPH clinical progression in patients .Conclusion FBS, FINS can contribute to clinical pro-gression in elderly patients with BPH .