中华临床医师杂志(电子版)
中華臨床醫師雜誌(電子版)
중화림상의사잡지(전자판)
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2015年
2期
304-308
,共5页
胰腺炎,急性坏死性%胰腺脑病%机制研究
胰腺炎,急性壞死性%胰腺腦病%機製研究
이선염,급성배사성%이선뇌병%궤제연구
Pancreatitis,acute necrotizing%Pancreatic encephalopathy%Mechanism research
胰腺脑病是重症急性胰腺炎的严重并发症,病死率高,预后差。目前关于胰腺脑病的发病机制主要有胰酶学说、细胞因子学说、营养缺乏学说、细菌和真菌感染学说、低氧血症与微循环障碍和组织代谢紊乱学说等,但尚未有哪一种学说能独立阐明其发病机制。笔者主要综述近几年来发展的各种学说。
胰腺腦病是重癥急性胰腺炎的嚴重併髮癥,病死率高,預後差。目前關于胰腺腦病的髮病機製主要有胰酶學說、細胞因子學說、營養缺乏學說、細菌和真菌感染學說、低氧血癥與微循環障礙和組織代謝紊亂學說等,但尚未有哪一種學說能獨立闡明其髮病機製。筆者主要綜述近幾年來髮展的各種學說。
이선뇌병시중증급성이선염적엄중병발증,병사솔고,예후차。목전관우이선뇌병적발병궤제주요유이매학설、세포인자학설、영양결핍학설、세균화진균감염학설、저양혈증여미순배장애화조직대사문란학설등,단상미유나일충학설능독립천명기발병궤제。필자주요종술근궤년래발전적각충학설。
Pancreatic encephalopathy (PE) is a severe complication of severe acute pancreatitis, and has the characteristics of the high mortality and poor prognosis. Although about the pathogenesis of pancreatic encephalopathy mainly include theory of pancreatic enzyme, the theory of cytokines, the theory of alimentary deficiency, the theory of bacterial and fungal infection, the theory of hypoxemia and microcirculation dysfunction, the theory of tissue metabolism disorder and so on, the pathogenesis of pancreatic encephalopathy still unclear at present. The author mainly reviews the development of the pathogenesis of pancreatic encephalopathy in recent years.