CAJ | 학술논문

甲状旁腺癌是少见的内分泌恶性肿瘤之一，其主要表现是甲状旁腺激素水平升高导致的高血钙症状和由于高钙血症引起的各种代谢紊乱以及相应组织器官的损害。完善的实验室检查、准确的影像学定位和可靠的组织病理学特征是甲状旁腺癌诊断的重要依据。甲状旁腺癌对放疗、化疗不敏感，肿瘤及其周围受侵组织的完整切除是首选的治疗方式。PTH诱导的免疫治疗作为一种新的治疗方法备受关注，预后主要取决于初次手术时肿物的完全切除及术后高钙血症的控制及监测。
갑상방선암시소견적내분비악성종류지일，기주요표현시갑상방선격소수평승고도치적고혈개증상화유우고개혈증인기적각충대사문란이급상응조직기관적손해。완선적실험실검사、준학적영상학정위화가고적조직병이학특정시갑상방선암진단적중요의거。갑상방선암대방료、화료불민감，종류급기주위수침조직적완정절제시수선적치료방식。PTH유도적면역치료작위일충신적치료방법비수관주，예후주요취결우초차수술시종물적완전절제급술후고개혈증적공제급감측。
Parathyroid carcinoma is a rare malignant endocrine tumor, its main performances are high blood calcium symptoms caused by elevated parathyroid hormone (PTH) and the corresponding damage of tissues and organs. Perfect laboratory examinations, the accurate imaging localization and reliable histopathological characteristics are the important basises of parathyroid carcinoma diagnosis. Parathyroid carcinoma is not sensitive to radiation therapy and chemotherapy, complete resection of tumor and its surrounding invaded organizations is the preferred treatment. Immunotherapy induced by PTH as a new method of treatment is paid more attention. Prognosis of the parathyroid carcinoma mainly depends on the complete resection of the tumor in the first operation and the control and the monitoring of hypercalcemia.