中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2015年
2期
218-222
,共5页
李绅%王美%耿顺玲%付锦华
李紳%王美%耿順玲%付錦華
리신%왕미%경순령%부금화
妊娠初期%超声检查,多普勒,彩色%流产,习惯性%妊娠结局%子宫动脉血流参数
妊娠初期%超聲檢查,多普勒,綵色%流產,習慣性%妊娠結跼%子宮動脈血流參數
임신초기%초성검사,다보륵,채색%유산,습관성%임신결국%자궁동맥혈류삼수
Pregnancy trimester,first%Ultrasonography,Doppler,color%Abortion,habitual%Pregnancy outcome%Uterine artery flow
目的：通过对育龄期正常及复发性流产（RSA）妇女备孕前1个月及孕后10周内子宫动脉血流（UtA）动力学系统相关指标的观察，了解月经周期的黄体期及孕10周内UtA动力学特点及其对妊娠结局的影响。方法将既往无不良妊娠史的育龄期妇女250例及既往有3次及以上自然流产的史妇女168例纳入研究，采用阴道超声于排卵后及孕10周内监测研究对象双侧子宫动脉血流动力学参数，测量参数包括搏动指数（PI）、阻力指数（RI）、收缩期峰值流速/舒张末期流速（S/D）；记录各组的PI、RI、S/D值，统计分析各组子宫动脉 PI、RI、S/D值的差异，比较妊娠丢失率的不同。结果孕前后或孕后子宫动脉血流异常者与正常者相比较，妊娠丢失率有统计学差异（P＜0.05）。孕前后或孕后子宫动脉血流值异常未治疗者与治疗后孕10周内恢复正常者比较，PI、RI、S/D及妊娠丢失率均有统计学差异（P＜0.05）。RSA 患者孕前异常血流经治疗后，孕后子宫动脉血流异常率降低、异常血流治疗恢复率升高，与孕前未纠正者相比较，有统计学差异（P＜0.05）。结论孕早期子宫动脉血流参数与妊娠结局有相关性。异常血流早期纠正，能显著改善妊娠结局。RSA患者孕前子宫动脉血流参数影响妊娠结局。
目的：通過對育齡期正常及複髮性流產（RSA）婦女備孕前1箇月及孕後10週內子宮動脈血流（UtA）動力學繫統相關指標的觀察，瞭解月經週期的黃體期及孕10週內UtA動力學特點及其對妊娠結跼的影響。方法將既往無不良妊娠史的育齡期婦女250例及既往有3次及以上自然流產的史婦女168例納入研究，採用陰道超聲于排卵後及孕10週內鑑測研究對象雙側子宮動脈血流動力學參數，測量參數包括搏動指數（PI）、阻力指數（RI）、收縮期峰值流速/舒張末期流速（S/D）；記錄各組的PI、RI、S/D值，統計分析各組子宮動脈 PI、RI、S/D值的差異，比較妊娠丟失率的不同。結果孕前後或孕後子宮動脈血流異常者與正常者相比較，妊娠丟失率有統計學差異（P＜0.05）。孕前後或孕後子宮動脈血流值異常未治療者與治療後孕10週內恢複正常者比較，PI、RI、S/D及妊娠丟失率均有統計學差異（P＜0.05）。RSA 患者孕前異常血流經治療後，孕後子宮動脈血流異常率降低、異常血流治療恢複率升高，與孕前未糾正者相比較，有統計學差異（P＜0.05）。結論孕早期子宮動脈血流參數與妊娠結跼有相關性。異常血流早期糾正，能顯著改善妊娠結跼。RSA患者孕前子宮動脈血流參數影響妊娠結跼。
목적：통과대육령기정상급복발성유산（RSA）부녀비잉전1개월급잉후10주내자궁동맥혈류（UtA）동역학계통상관지표적관찰，료해월경주기적황체기급잉10주내UtA동역학특점급기대임신결국적영향。방법장기왕무불량임신사적육령기부녀250례급기왕유3차급이상자연유산적사부녀168례납입연구，채용음도초성우배란후급잉10주내감측연구대상쌍측자궁동맥혈류동역학삼수，측량삼수포괄박동지수（PI）、조력지수（RI）、수축기봉치류속/서장말기류속（S/D）；기록각조적PI、RI、S/D치，통계분석각조자궁동맥 PI、RI、S/D치적차이，비교임신주실솔적불동。결과잉전후혹잉후자궁동맥혈류이상자여정상자상비교，임신주실솔유통계학차이（P＜0.05）。잉전후혹잉후자궁동맥혈류치이상미치료자여치료후잉10주내회복정상자비교，PI、RI、S/D급임신주실솔균유통계학차이（P＜0.05）。RSA 환자잉전이상혈류경치료후，잉후자궁동맥혈류이상솔강저、이상혈류치료회복솔승고，여잉전미규정자상비교，유통계학차이（P＜0.05）。결론잉조기자궁동맥혈류삼수여임신결국유상관성。이상혈류조기규정，능현저개선임신결국。RSA환자잉전자궁동맥혈류삼수영향임신결국。
Objective To identify the relationship between uterine artery blood flow and pregnancy outcome, and to comprehend the uterine artery blood flow velocity characteristics of luteal phase of the menstrual cycle and pregnancy 10 weeks. Methods 250 subjects with no previous history of adverse pregnancy and 168 subjects with more than three times of spontaneous abortion were included. Monitored the bilateral uterine artery blood flow velocity parameters, which included pulsatility index (PI), resistance index (RI), and peak systolic velocity/diastolic velocity (S/D), using transvaginal ultrasound at 10 weeks of pregnancy and after ovulation. The values of PI, RI, and S/D were recorded. Results Pregnancy loss rates had significant difference between subjects of abnormal uterine artery blood flow and normal controls (P<0.05);PI, RI, and S/D values and pregnancy loss rate were all significantly different between subjects of abnormal uterine artery blood flow with systematic treatment after pregnancy and without treatment;The rate of abnormal uterine artery blood flow was decreased and the treatment recovery rate of uterine artery blood flow was increased after treatment. Conclusions Uterine artery blood flow parameters of trimester correlated with pregnancy outcomes;Treating abnormal blood flow earlier can significantly improve pregnancy outcomes; Pre-pregnancy uterine artery blood flow parameters of recurrent abortion can affect pregnancy outcomes.
