CAJ | 학술논문

目的：探讨降钙素原（PCT）、前清蛋白（PA）和白细胞（WBC）检测在儿童感染性疾病诊断中的临床应用。方法选取因感染性疾病来该院儿科住院治疗的儿童116例进行研究，根据病原微生物的不同分为非细菌组（56例）和细菌组（60例），另设在本院儿科门诊体检的健康儿童64例为对照组，对各组儿童血液 PCT、PA 水平进行检测和 WBC 计数，同时检测细菌组治疗前和治疗后的 PCT、PA 水平和 WBC 计数，分别比较各组水平的差异。结果细菌和非细菌组患儿血液 PCT 和 WBC 计数值均高于对照组，而细菌组 PA 水平低于非细菌组和对照组，差异具有统计学意义（P ＜0．05）；细菌组治疗后的 PCT 水平和 WBC 计数低于治疗前，而 PA 治疗后的水平要高于治疗前，差异有统计学意义（P ＜0．05）。结论 PCT、PA 和 WBC 计数的检测可作为儿童感染性疾病的诊断指标，同时为预后的判断提供参考。
목적：탐토강개소원（PCT）、전청단백（PA）화백세포（WBC）검측재인동감염성질병진단중적림상응용。방법선취인감염성질병래해원인과주원치료적인동116례진행연구，근거병원미생물적불동분위비세균조（56례）화세균조（60례），령설재본원인과문진체검적건강인동64례위대조조，대각조인동혈액 PCT、PA 수평진행검측화 WBC 계수，동시검측세균조치료전화치료후적 PCT、PA 수평화 WBC 계수，분별비교각조수평적차이。결과세균화비세균조환인혈액 PCT 화 WBC 계수치균고우대조조，이세균조 PA 수평저우비세균조화대조조，차이구유통계학의의（P ＜0．05）；세균조치료후적 PCT 수평화 WBC 계수저우치료전，이 PA 치료후적수평요고우치료전，차이유통계학의의（P ＜0．05）。결론 PCT、PA 화 WBC 계수적검측가작위인동감염성질병적진단지표，동시위예후적판단제공삼고。
Objective To investigate the clinical application of procalcitonin (PCT),pre-albumin (PA)and white blood cell (WBC)detections in children infectious diseases.Methods 116 children inpatients of infectious diseases in our hospital were select-ed for conducting the study and divided into the non-bacterial infection group (56 cases)and the bacterial infection group (60 cases) according to the different pathogenic microorganisms.Other 64 children with healthy physical examination in the outpatient depart-ment were taken as the control group.The blood PCT,PA levels and WBC count were detected in 3 groups,and which before and after treatment in the bacterial infection group were detected.The differences in PCT,PA levels and WBC count were compared a-mong the groups.Results The blood PCT level and WBC count in the bacterial infection group and the non-bacterial infection group were all higher than that in the control group,while the PA level in the bacterial infection group was lower than that in the non-bacterial infection group and the control group,the differences had statistical significance (P <0.05);the PCT level and WBC count after treatment in the bacterial infection groups were lower than those before treatment,while the PA level after treatment was higher than that before treatment with statistical difference (P <0.05).Conclusion The detection of PCT,PA and WBC count can be used as the indexes for diagnosing infectious diseases in children,and provides reference for the judgment of prognosis.