CAJ | 학술논문

目的：探讨围术期高龄髋部骨折患者血液中 D-二聚体（D-D）水平的变化及其临床意义。方法对60例80岁以上髋部骨折患者手术前、手术后血液中 D-D 水平进行检测。手术前包括入院时（T1）、即将手术时（T2），T 后包括手术后即刻（T3）和手术后第1天（T4）。结果 T1、T2、T3、T4 D-D 阳性率分别为6．67％、16．67％、41．67％、80．00％，T3、T4与 T1、T2相比，T3与T4相比，差异均有统计学意义（P ＜0．05）；T1与 T2相比，差异无统计学意义（P ＞0．05）。结论高龄髋部骨折患者手术前后 D-D水平变化显著，D-D 水平的变化是反映下肢深静脉血栓的有效指标，对于高龄髋部骨折患者围术期进行 D-D 水平动态监测有着极其重要的临床意义。
목적：탐토위술기고령관부골절환자혈액중 D-이취체（D-D）수평적변화급기림상의의。방법대60례80세이상관부골절환자수술전、수술후혈액중 D-D 수평진행검측。수술전포괄입원시（T1）、즉장수술시（T2），T 후포괄수술후즉각（T3）화수술후제1천（T4）。결과 T1、T2、T3、T4 D-D 양성솔분별위6．67％、16．67％、41．67％、80．00％，T3、T4여 T1、T2상비，T3여T4상비，차이균유통계학의의（P ＜0．05）；T1여 T2상비，차이무통계학의의（P ＞0．05）。결론고령관부골절환자수술전후 D-D수평변화현저，D-D 수평적변화시반영하지심정맥혈전적유효지표，대우고령관부골절환자위술기진행 D-D 수평동태감측유착겁기중요적림상의의。
Objective To investigate the change and clinical significance of blood D-dimer level during perioperative period in ad-vanced age hip fracture.Methods The blood D-dimer level in 60 patients aged over 80 years old with hip fracture was detected be-fore operation and after operation,which including at admission(T1 ),immediately preoperation(T2 ),immediately postoperation (T3 )and on postoperative 1 d (T4 ).Results The positive rates of D-dimer at T1 ,T2 ,T3 and T4 were 6.67%,16.45%,41.67%and 80.00% respectively;there were statistically significant differences between T3 ,T4 and T1 ,T2 ,between T3 and T4 (P <0.05);there was no statistically significant difference between T1 and T2 (P >0.05).Conclusion The level of D-dimer in advanced age hip fracture has significant change before and after operation.The change of the D-dimer positive rate is an effective index for preven-ting lower limbs deep venous thrombosis and has the important clinical significance to dynamically monitor the D-dimer level during perioperative period in advanced age hip fracture.