CAJ | 학술논문

目的：观察磷酸肌酸钠对老老年严重肺部感染合并心力衰竭患者血浆 N末端B型钠尿肽前体（ NT-proBNP）的影响。方法将80岁以上老老年肺部感染并发心力衰竭30例患者，随机分为观察组和对照组各15例。对照组采用常规抗感染及抗心力衰竭治疗。观察组在对照组治疗基础上加用磷酸肌酸钠治疗，观察治疗1周后NT-proBNP的变化。结果2组治疗1周后，NT-proBNP水平均低于治疗前，且观察组下降幅度大于对照组，差异均有统计学意义（ P＜0.05或P＜0.01）。结论磷酸肌酸钠能迅速降低老老年严重肺部感染并发心力衰竭的NT-proBNP水平，改善全身状况。
목적：관찰린산기산납대로노년엄중폐부감염합병심력쇠갈환자혈장 N말단B형납뇨태전체（ NT-proBNP）적영향。방법장80세이상로노년폐부감염병발심력쇠갈30례환자，수궤분위관찰조화대조조각15례。대조조채용상규항감염급항심력쇠갈치료。관찰조재대조조치료기출상가용린산기산납치료，관찰치료1주후NT-proBNP적변화。결과2조치료1주후，NT-proBNP수평균저우치료전，차관찰조하강폭도대우대조조，차이균유통계학의의（ P＜0.05혹P＜0.01）。결론린산기산납능신속강저로노년엄중폐부감염병발심력쇠갈적NT-proBNP수평，개선전신상황。
Objective To observe the effect of creatine phosphate sodium on NT-proBNP levels of very elderly pa-tients with severe pulmonary infection and heart failure. Methods The 30 patients with serious pulmonary infection and heart failure were randomly divided into observation group and control group,each of 15 cases. The control group were received con-ventional treatment,and the observation group were given the Creatine phosphate sodium based on the conventional treatment. After a week of treatment,observed the BNP level changes of the two groups. Results BNP was to some extent decline in both groups(P<0. 05),and the observation group's BNP was significantly lower than the control group's(P<0. 05). Conclusion Creatine phosphate sodium can reduce BNP level in very elderly patients with severe pulmonary infection and heart failure, and improve the general condition of patients.