四川医学
四川醫學
사천의학
SICHUAN MEDICAL JOURNAL
2015年
1期
11-13,14
,共4页
陈祥吉%黄晓波%刘雅%欧阳凌云%王宾友%马艳%吕艳%魏东%王琼%杨雷%张馨予
陳祥吉%黃曉波%劉雅%歐暘凌雲%王賓友%馬豔%呂豔%魏東%王瓊%楊雷%張馨予
진상길%황효파%류아%구양릉운%왕빈우%마염%려염%위동%왕경%양뢰%장형여
糖耐量正常%糖化血红蛋白%参考范围%流行病学
糖耐量正常%糖化血紅蛋白%參攷範圍%流行病學
당내량정상%당화혈홍단백%삼고범위%류행병학
normal glucose tolerance%glycated hemoglobin%reference range%epidemiology
目的：建立成都地区中老年糖耐量正常人群糖化血红蛋白( HbA1c)的参考范围。方法采用分层随机抽样的方法,对成都城市社区1025例中老年人开展横断面流行病学调查,进行OGTT、HbA1c、血压及血脂等检测,予以统一的问卷调查,对其中647例正常糖耐量人群采用正态分布法的95%CI确定HbA1c参考值范围。结果糖耐量正常人群的HbA1c呈近似正态分布,647例中老年正常糖耐量人群HbA1c参考范围5．02%~6．28%,其中男性糖化血红蛋白平均值为5．67%,女性为5．64%,两者差异无统计学意义(F=2．363,P=0．095)。结论成都地区中老年糖耐量正常人群HbA1c参考范围5．02%~6．28%。中老年个体HbA1c超过此范围,需进一步行OGTT明确是否有糖尿病或处于糖尿病前期。
目的：建立成都地區中老年糖耐量正常人群糖化血紅蛋白( HbA1c)的參攷範圍。方法採用分層隨機抽樣的方法,對成都城市社區1025例中老年人開展橫斷麵流行病學調查,進行OGTT、HbA1c、血壓及血脂等檢測,予以統一的問捲調查,對其中647例正常糖耐量人群採用正態分佈法的95%CI確定HbA1c參攷值範圍。結果糖耐量正常人群的HbA1c呈近似正態分佈,647例中老年正常糖耐量人群HbA1c參攷範圍5．02%~6．28%,其中男性糖化血紅蛋白平均值為5．67%,女性為5．64%,兩者差異無統計學意義(F=2．363,P=0．095)。結論成都地區中老年糖耐量正常人群HbA1c參攷範圍5．02%~6．28%。中老年箇體HbA1c超過此範圍,需進一步行OGTT明確是否有糖尿病或處于糖尿病前期。
목적：건립성도지구중노년당내량정상인군당화혈홍단백( HbA1c)적삼고범위。방법채용분층수궤추양적방법,대성도성시사구1025례중노년인개전횡단면류행병학조사,진행OGTT、HbA1c、혈압급혈지등검측,여이통일적문권조사,대기중647례정상당내량인군채용정태분포법적95%CI학정HbA1c삼고치범위。결과당내량정상인군적HbA1c정근사정태분포,647례중노년정상당내량인군HbA1c삼고범위5．02%~6．28%,기중남성당화혈홍단백평균치위5．67%,녀성위5．64%,량자차이무통계학의의(F=2．363,P=0．095)。결론성도지구중노년당내량정상인군HbA1c삼고범위5．02%~6．28%。중노년개체HbA1c초과차범위,수진일보행OGTT명학시부유당뇨병혹처우당뇨병전기。
Objective To establish a glycosylated hemoglobin reference range in normal glucose tolerance of the mid-dle-aged and old people in Chengdu area. Methods Strta randomized sampling method was used to investigate the cross-sectional study of epidemiology of the 1,025 middle-aged and old people in the comunity of Chengdu city, including the test of OGTT, HbA1c, blood plessure, blood fat, etc. and unifying the questionnaires for them. And 647 middle-aged and old people in normal glucose tolerance were tested by the 95% confidence interval of the normal distribution method to ensure the reference range of the HbA1c. Result The HbA1c of the glucose tolerance of normal crowd appeared normal distribution. The reference range was 5. 02% ~6. 28% among the 647 middle-aged and old people’s HbA1c in the glycosylated hemoglobin in normal glucose tolerance. The glycated hemoglobin of average value was 5. 67% for men and that of 5. 64% for women. There was no significant difference (F=2. 363, P=0. 095, P>0. 05). Conclusion The reference range is 5. 02% ~6. 28% in normal glucose tolerance of the middle-aged and old people’s HbA1c in Chengdu area. If their HbA1c is beyond this scope, they need to have OGTT to ensure whether there is sugar metabolic abnormalities.
