中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2015年
2期
188-191
,共4页
胰升糖素样肽 1%内质网应激
胰升糖素樣肽 1%內質網應激
이승당소양태 1%내질망응격
Glucagon-like peptide-1%Endoplasmic reticulum stress
胰升糖素样肽1(glucagon-like peptide-1, GLP-1)是一种经食物刺激后主要由回肠末端、结肠和直肠中 L 细胞产生和分泌的肠促胰岛素,它可以与体内 GLP-1受体结合,发挥一系列的生物学效应。近年来研究表明,GLP-1通过减少内质网应激,参与了多种疾病的发生及发展。
胰升糖素樣肽1(glucagon-like peptide-1, GLP-1)是一種經食物刺激後主要由迴腸末耑、結腸和直腸中 L 細胞產生和分泌的腸促胰島素,它可以與體內 GLP-1受體結閤,髮揮一繫列的生物學效應。近年來研究錶明,GLP-1通過減少內質網應激,參與瞭多種疾病的髮生及髮展。
이승당소양태1(glucagon-like peptide-1, GLP-1)시일충경식물자격후주요유회장말단、결장화직장중 L 세포산생화분비적장촉이도소,타가이여체내 GLP-1수체결합,발휘일계렬적생물학효응。근년래연구표명,GLP-1통과감소내질망응격,삼여료다충질병적발생급발전。
Glucagon-like peptide-1(GLP-1) is an incretin stimulated by food mainly produced and secreted from L-cells in terminal ileum, colon and rectum. It can be combined with GLP-1 receptors, and then plays a series of biological effects. In recent years, studies have shown that GLP-1 participates in the occurrence and development of many diseases.