中国性科学
中國性科學
중국성과학
THE CHINESE JOURNAL OF HUMAN SEXUALITY
2015年
2期
11-14
,共4页
液基薄层细胞学检查%阴道镜活检%宫颈癌
液基薄層細胞學檢查%陰道鏡活檢%宮頸癌
액기박층세포학검사%음도경활검%궁경암
Liquid thin -layer cytology%Colposcopy biopsy%Cervical cancer
目的:探讨液基薄层细胞学检查与阴道镜活检在宫颈癌诊断中的临床诊断效果。方法:选取2013年4月至2014年4月在我院妇科门诊接受宫颈癌筛查的1434患者为研究对象,对采取宫颈液基薄层细胞学检查(TCT)后结果呈阳性的202例患者行阴道镜下宫颈活检,对比诊断结果。结果:参与本次宫颈癌筛查的1434患者中,病理检验正常或炎症者1200例,阴性率为837%,检测结果呈阳性者234例,阳性率为163%;TCT检查结果呈阳性的患者202例,阳性检出率为863%,其中诊断结果为ASC-US、LSIL、HSIL或SCC者分别125例(619%)、53例(262%)、20例(99%)和4例(20%),两组检测方法对比无明显差异,P>005;阴道镜下活检结果与TCT检查结果相符率分别为SCC25%(1/4)、HSIL60%(12/20)、LSIL66%(35/53);ASC-US结果中,阴道镜下活检CINⅠ48例、CINⅡ7例、CINⅢ3例,共58例,占例数的464%。结论:液基薄层细胞学检查能有效提升宫颈癌及宫颈上皮内病变(CIN)等癌前病变检出率,对宫颈癌早期诊断意义重大。对于TCT检查结果为无明确意义的非典型细胞改变(ASC-US)患者,应引起临床重视,根据患者病情行阴道镜检查,以提升宫颈癌及癌前病变诊断准确率,争取宝贵的治疗时间。
目的:探討液基薄層細胞學檢查與陰道鏡活檢在宮頸癌診斷中的臨床診斷效果。方法:選取2013年4月至2014年4月在我院婦科門診接受宮頸癌篩查的1434患者為研究對象,對採取宮頸液基薄層細胞學檢查(TCT)後結果呈暘性的202例患者行陰道鏡下宮頸活檢,對比診斷結果。結果:參與本次宮頸癌篩查的1434患者中,病理檢驗正常或炎癥者1200例,陰性率為837%,檢測結果呈暘性者234例,暘性率為163%;TCT檢查結果呈暘性的患者202例,暘性檢齣率為863%,其中診斷結果為ASC-US、LSIL、HSIL或SCC者分彆125例(619%)、53例(262%)、20例(99%)和4例(20%),兩組檢測方法對比無明顯差異,P>005;陰道鏡下活檢結果與TCT檢查結果相符率分彆為SCC25%(1/4)、HSIL60%(12/20)、LSIL66%(35/53);ASC-US結果中,陰道鏡下活檢CINⅠ48例、CINⅡ7例、CINⅢ3例,共58例,佔例數的464%。結論:液基薄層細胞學檢查能有效提升宮頸癌及宮頸上皮內病變(CIN)等癌前病變檢齣率,對宮頸癌早期診斷意義重大。對于TCT檢查結果為無明確意義的非典型細胞改變(ASC-US)患者,應引起臨床重視,根據患者病情行陰道鏡檢查,以提升宮頸癌及癌前病變診斷準確率,爭取寶貴的治療時間。
목적:탐토액기박층세포학검사여음도경활검재궁경암진단중적림상진단효과。방법:선취2013년4월지2014년4월재아원부과문진접수궁경암사사적1434환자위연구대상,대채취궁경액기박층세포학검사(TCT)후결과정양성적202례환자행음도경하궁경활검,대비진단결과。결과:삼여본차궁경암사사적1434환자중,병리검험정상혹염증자1200례,음성솔위837%,검측결과정양성자234례,양성솔위163%;TCT검사결과정양성적환자202례,양성검출솔위863%,기중진단결과위ASC-US、LSIL、HSIL혹SCC자분별125례(619%)、53례(262%)、20례(99%)화4례(20%),량조검측방법대비무명현차이,P>005;음도경하활검결과여TCT검사결과상부솔분별위SCC25%(1/4)、HSIL60%(12/20)、LSIL66%(35/53);ASC-US결과중,음도경하활검CINⅠ48례、CINⅡ7례、CINⅢ3례,공58례,점례수적464%。결론:액기박층세포학검사능유효제승궁경암급궁경상피내병변(CIN)등암전병변검출솔,대궁경암조기진단의의중대。대우TCT검사결과위무명학의의적비전형세포개변(ASC-US)환자,응인기림상중시,근거환자병정행음도경검사,이제승궁경암급암전병변진단준학솔,쟁취보귀적치료시간。
Objectives:To investigate the diagnostic effect of liquid thin -layer cytology and colposcopy bi-opsy in the diagnosis of cervical cancer.Method:1434 patients received cervical cancer screening selection from A-pril 2013 -April 2014 in outpatient of gynaecology in our hospital were selected as the research objects.202 pa-tients with a positive result of cervical liquid thin -layer cytology (TCT)received cervical biopsy under colposcopy to compare the diagnosis results.Results:Among the 1434 patients received cervical cancer screening,there were 1200 cases with normal and inflammation results in pathological examination,a negative rate of 83.7%.There were 234 cases with positive test results,a positive rate of 16.3%;there were 202 patients with positive TCT examination results,a positive detection rate of 86.3%.Among them,the diagnosis results of ASC -US,LSIL,HSIL or SCC were 125 cases (61.9%),53 cases (26.2%),20 cases (9.9%)and 4 cases (2.0%)respectively,without sig-nificant difference,P > 0.05;the consistency rates of biopsy colposcope results and TCT results rate were HSIL60%(12 /20),SCC25%(1 /4)and LSIL66%(35 /53)respectively;In ASC -US results,biopsy under col-poscopy,there were 48 cases CIN,7 cases CIN,3 cases CIN Ⅲ,58 cases in total,accounting for 46.4%.Con-clusion:Liquid based thin -layer cytology can effectively improve the detection rate of cervical cancer and cervical intraepithelial lesion (CIN)and precancerous lesion,which is of great significance to early cervical cancer diagno-sis.Patients with atypical cells change (ASC -US)with no clear meaning of TCT should be paid attention.Ac-cording to patient condition,colposcopy examination can enhance the diagnosis accuracy of cervical cancer and pre-cancerous lesion.