中国性科学
中國性科學
중국성과학
THE CHINESE JOURNAL OF HUMAN SEXUALITY
2015年
2期
53-56
,共4页
鞠小玲%杜坤%程丰%苏江维
鞠小玲%杜坤%程豐%囌江維
국소령%두곤%정봉%소강유
苄星青霉素%头孢曲松钠%早期梅毒%皮损%血液%免疫指标
芐星青黴素%頭孢麯鬆鈉%早期梅毒%皮損%血液%免疫指標
변성청매소%두포곡송납%조기매독%피손%혈액%면역지표
Benzathine benzylpenicillin%Ceftriaxone sodium%Early syphilis%Skin lesion%Blood immune indexes
目的：观察苄星青霉素联合头孢曲松钠对早期梅毒患者皮损及血液免疫指标的影响程度。方法：选取2011年3月至2013年8月于本院进行诊治的60例早期梅毒患者为研究对象，将60例患者随机分为对照组（苄星青霉素组）30例和观察组（苄星青霉素联合头孢曲松钠组）30例，然后将两组患者治疗前和治疗后1 个月、3 个月时的红细胞免疫、皮损及外周血T 淋巴细胞亚群指标进行检测与比较。结果：观察组治疗后1 个月及3 个月时的红细胞免疫及外周血CD3 ＋、CD4 ＋、CD4 ／CD8 均高于对照组，而CD8 ＋均低于对照组，皮损CD3 ＋、CD4 ＋、CD4 ／CD8 均低于对照组，而CD8 ＋均高于对照组，P ＜005，均有显著性差异。结论：苄星青霉素联合头孢曲松钠对早期梅毒患者皮损及血液免疫指标的影响较大，对患者的治疗效果好于单用苄星青霉素。
目的：觀察芐星青黴素聯閤頭孢麯鬆鈉對早期梅毒患者皮損及血液免疫指標的影響程度。方法：選取2011年3月至2013年8月于本院進行診治的60例早期梅毒患者為研究對象，將60例患者隨機分為對照組（芐星青黴素組）30例和觀察組（芐星青黴素聯閤頭孢麯鬆鈉組）30例，然後將兩組患者治療前和治療後1 箇月、3 箇月時的紅細胞免疫、皮損及外週血T 淋巴細胞亞群指標進行檢測與比較。結果：觀察組治療後1 箇月及3 箇月時的紅細胞免疫及外週血CD3 ＋、CD4 ＋、CD4 ／CD8 均高于對照組，而CD8 ＋均低于對照組，皮損CD3 ＋、CD4 ＋、CD4 ／CD8 均低于對照組，而CD8 ＋均高于對照組，P ＜005，均有顯著性差異。結論：芐星青黴素聯閤頭孢麯鬆鈉對早期梅毒患者皮損及血液免疫指標的影響較大，對患者的治療效果好于單用芐星青黴素。
목적：관찰변성청매소연합두포곡송납대조기매독환자피손급혈액면역지표적영향정도。방법：선취2011년3월지2013년8월우본원진행진치적60례조기매독환자위연구대상，장60례환자수궤분위대조조（변성청매소조）30례화관찰조（변성청매소연합두포곡송납조）30례，연후장량조환자치료전화치료후1 개월、3 개월시적홍세포면역、피손급외주혈T 림파세포아군지표진행검측여비교。결과：관찰조치료후1 개월급3 개월시적홍세포면역급외주혈CD3 ＋、CD4 ＋、CD4 ／CD8 균고우대조조，이CD8 ＋균저우대조조，피손CD3 ＋、CD4 ＋、CD4 ／CD8 균저우대조조，이CD8 ＋균고우대조조，P ＜005，균유현저성차이。결론：변성청매소연합두포곡송납대조기매독환자피손급혈액면역지표적영향교대，대환자적치료효과호우단용변성청매소。
Objectives:To observe the influence of benzathine benzylpenicillin combined with ceftriaxone sodium for the skin lesion and blood immune indexes of patients with early syphilis.Methods:60 patients with ear-ly syphilis in our hospital from March 2011 to August 2013 were selected and randomly divided into control group (benzathine benzylpenicillin group,30 cases)and observation group (benzathine benzylpenicillin combined with ceftriaxone sodium group,30 cases).The erythrocyte immune,skin lesion and peripheral blood T lymphocyte sub-sets of two groups before the treatment and at first and third month after the treatment were detected and compared. Results:The erythrocyte immune and peripheral blood CD3 +,CD4 +,CD4 /CD8 of observation group at first and third month after the treatment were all higher than those of control group,while CD8 + were lower than those of control group,and skin lesion CD3 +,CD4 +and CD4 /CD8 were lower than those of control group,CD8 +were higher than those of control group,with significant differences (all P <0.05 ).Conclusion:The influence of benzathine benzylpenicillin combined with ceftriaxone sodium for the skin lesion and blood immune indexes of pa-tients with early syphilis is great,and its treatment effect for the patients is better than that of only benzathine benzylpenicillin.
