CAJ | 학술논문

应激性胃溃疡是由于应激引起的以胃黏膜糜烂、表浅溃疡以及胃黏膜出血为特征的应激胃黏膜病变。其发病原因与生活息息相关，发病人数日益增多。近年来相应的药物基础研究主要围绕着抑制应激所造成的氧化损伤、抗炎症因子的表达、调节胃酸等，并取得大量的研究成果，对于治疗应激性胃溃疡的药物选择逐渐多样化，植物提取物对应激性胃溃疡的作用得到越来越多的关注。文中就目前对应激性胃溃疡的药物治疗研究情况作一综述。
응격성위궤양시유우응격인기적이위점막미란、표천궤양이급위점막출혈위특정적응격위점막병변。기발병원인여생활식식상관，발병인수일익증다。근년래상응적약물기출연구주요위요착억제응격소조성적양화손상、항염증인자적표체、조절위산등，병취득대량적연구성과，대우치료응격성위궤양적약물선택축점다양화，식물제취물대응격성위궤양적작용득도월래월다적관주。문중취목전대응격성위궤양적약물치료연구정황작일종술。
The stress gastric ulcer is due to a stress-induced gastric erosions, superficial ulcers and bleeding gastric mucosal le-sions characterized by stress. Its etiology is closely associated with lives, the incidence is increasing. In recent years, the the basic re-search of drugs focuses on inhibition of oxidative damage caused by stress, anti-inflammatory cytokine expression, and regulation of gastric acid, etc., and made a lot of success. Treatment choice of stress ulcer drug gradually increased. The effects of plant extracts on stress ul-cer get more and more attention. This article reviews research progress of the treatment drugs of stress ulcer in the current stage.