CAJ | 학술논문

癌症是世界上发病率和病死率最高的疾病之一，随着生活方式的变化和社会老龄化，防治癌症的任务将十分艰巨。早期诊断方法存在阳性率低、过度诊断及有创等缺点，不利于高危人群筛查及癌症生存率的提高。拉曼光谱技术可以提供检测样本的分子结构特征，适合于癌症的早期诊断，且具有快速、无创及高灵敏度的特点，正在成为一种新的癌症诊断方法。通过介绍国内外拉曼光谱技术在癌症诊断方面的研究进展，提出采用唾液表面增强拉曼检测技术为癌症的筛查和早期诊断提供新途径的发展思路。
암증시세계상발병솔화병사솔최고적질병지일，수착생활방식적변화화사회노령화，방치암증적임무장십분간거。조기진단방법존재양성솔저、과도진단급유창등결점，불리우고위인군사사급암증생존솔적제고。랍만광보기술가이제공검측양본적분자결구특정，괄합우암증적조기진단，차구유쾌속、무창급고령민도적특점，정재성위일충신적암증진단방법。통과개소국내외랍만광보기술재암증진단방면적연구진전，제출채용타액표면증강랍만검측기술위암증적사사화조기진단제공신도경적발전사로。
Cancer is one of the diseases with highest incidence and mortality in the world, with the change of life style and the aging society, the task of prevention and treatment of cancer will be very difficult. The early diagnosis methods have the low positive rate, excessive diagnosis, invasive and other shortcomings, which is not conducive to the high-risk population screening and to improve the survival rate of cancer patients. Raman spectroscopy can provide the molecular structure characteristics of the test sample. It is very suitable for the early diagnosis of cancer. Raman spectrum detection technology, rapid, noninvasive and high sensitivity, is becoming a new method for cancer diagnosis. It mainly introduces the progress of Raman spectroscopy in cancer diagnosis and offers the new trends and the developing way for early diagnosis of cancer on saliva surface enhanced Raman spectroscopy technology.