中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2015年
1期
41-42,43
,共3页
溃疡散胶囊%薄层色谱法%高效液相色谱法%质量标准
潰瘍散膠囊%薄層色譜法%高效液相色譜法%質量標準
궤양산효낭%박층색보법%고효액상색보법%질량표준
Kuiyangsan Capsule%TLC%HPLC%quality standard
目的：提高溃疡散胶囊的质量标准。方法采用薄层色谱（TLC）法鉴别溃疡散胶囊中的黄芩、甘草，并用高效液相色谱法测定甘草中甘草酸的含量。结果 TLC法定性鉴别重复性好，阴性无干扰；甘草酸铵进样量在0.1496~1.7952μg（ r=0.9999）范围内与峰面积积分值呈良好的线性关系，平均回收率为102.52%，RSD=1.09%( n=6)。结论该法操作简便、重复性好，结果准确可靠，可用于溃疡散胶囊的质量控制。
目的：提高潰瘍散膠囊的質量標準。方法採用薄層色譜（TLC）法鑒彆潰瘍散膠囊中的黃芩、甘草，併用高效液相色譜法測定甘草中甘草痠的含量。結果 TLC法定性鑒彆重複性好，陰性無榦擾；甘草痠銨進樣量在0.1496~1.7952μg（ r=0.9999）範圍內與峰麵積積分值呈良好的線性關繫，平均迴收率為102.52%，RSD=1.09%( n=6)。結論該法操作簡便、重複性好，結果準確可靠，可用于潰瘍散膠囊的質量控製。
목적：제고궤양산효낭적질량표준。방법채용박층색보（TLC）법감별궤양산효낭중적황금、감초，병용고효액상색보법측정감초중감초산적함량。결과 TLC법정성감별중복성호，음성무간우；감초산안진양량재0.1496~1.7952μg（ r=0.9999）범위내여봉면적적분치정량호적선성관계，평균회수솔위102.52%，RSD=1.09%( n=6)。결론해법조작간편、중복성호，결과준학가고，가용우궤양산효낭적질량공제。
Objective To study the quality standard of Kuiyangsan Capsule. Methods The thin layer chromatography ( TLC ) was adopted to identify Radix scutellariae and Radix et rhizoma glycyrrhiza. The glycyrrhizinate content from Radix et rhizoma glycyrrhiza was deter-mined by HPLC. Results The TLC qualitative identification had good reproducibility without the negative interference. The linear range of glycyrrhizinate was 0. 149 6-1. 795 2 μg ( r=0. 999 9 ) . The average recovery rate was 102. 52%, RSD=1. 09% ( n=6 ) . Conclusion The established method is simple to operate, better repeatable, accurate and reliable in detection results, and can be used in the quality control of Kuiyangsan Capsule.
