中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2015年
1期
23-24,25
,共3页
肺动脉高压%新生儿%伊洛前列素%一氧化氮%吸入
肺動脈高壓%新生兒%伊洛前列素%一氧化氮%吸入
폐동맥고압%신생인%이락전렬소%일양화담%흡입
pulmonary arterial hypertension%newborn%iloprost%nitric oxide%inhalation
目的：探讨吸入伊洛前列素和一氧化氮治疗新生儿肺动脉高压的临床疗效及护理对策。方法选取肺动脉高压新生儿50例，随机分为研究组和对照组，各25例。两组患儿均给予基础治疗和一氧化氮吸入治疗，研究组患儿加用伊洛前列素雾化吸入。比较两组患儿的气道压力、血气指标和血流动力学指标。结果治疗后，两组患儿平均气道压力均显著降低，研究组低于对照组；氧合指数和血氧饱和度均显著提高，研究组显著高于对照组；肺动脉收缩压均显著降低，研究组显著低于对照组。以上比较，差异均有统计学意义（ P<0.05）。两组患儿治疗前后血压比较，差异无统计学意义（ P>0.05）。结论新生儿肺动脉高压患儿吸入伊洛前列素和一氧化氮可有效降低气道压力和肺动脉收缩压、提高氧合水平，合理的护理方法能进一步提高疗效。
目的：探討吸入伊洛前列素和一氧化氮治療新生兒肺動脈高壓的臨床療效及護理對策。方法選取肺動脈高壓新生兒50例，隨機分為研究組和對照組，各25例。兩組患兒均給予基礎治療和一氧化氮吸入治療，研究組患兒加用伊洛前列素霧化吸入。比較兩組患兒的氣道壓力、血氣指標和血流動力學指標。結果治療後，兩組患兒平均氣道壓力均顯著降低，研究組低于對照組；氧閤指數和血氧飽和度均顯著提高，研究組顯著高于對照組；肺動脈收縮壓均顯著降低，研究組顯著低于對照組。以上比較，差異均有統計學意義（ P<0.05）。兩組患兒治療前後血壓比較，差異無統計學意義（ P>0.05）。結論新生兒肺動脈高壓患兒吸入伊洛前列素和一氧化氮可有效降低氣道壓力和肺動脈收縮壓、提高氧閤水平，閤理的護理方法能進一步提高療效。
목적：탐토흡입이락전렬소화일양화담치료신생인폐동맥고압적림상료효급호리대책。방법선취폐동맥고압신생인50례，수궤분위연구조화대조조，각25례。량조환인균급여기출치료화일양화담흡입치료，연구조환인가용이락전렬소무화흡입。비교량조환인적기도압력、혈기지표화혈류동역학지표。결과치료후，량조환인평균기도압력균현저강저，연구조저우대조조；양합지수화혈양포화도균현저제고，연구조현저고우대조조；폐동맥수축압균현저강저，연구조현저저우대조조。이상비교，차이균유통계학의의（ P<0.05）。량조환인치료전후혈압비교，차이무통계학의의（ P>0.05）。결론신생인폐동맥고압환인흡입이락전렬소화일양화담가유효강저기도압력화폐동맥수축압、제고양합수평，합리적호리방법능진일보제고료효。
Objective To study the clinical efficacy and nursing strategy of the iloprost and NO inhalation for treating neonatal pul-monary hypertension. Methods A total of 50 neonates with pulmonary hypertension were selected and randomly divided into the study group and the control group, 25 cases in each group. The two groups were given the therapy of the basic treatment and nitric oxide ( NO ) inhalation, while the study group was added with the iloprost nebulization inhalation. The airway pressure, blood gas indices and hemodynamic indices were compared between the two groups. Results The mean airway pressure after treatment in the two groups was significantly decreased;the oxygenation index and blood oxygen saturation were significantly increased, and the data in the study group were significantly higher than those in the control group;the pulmonary artery systolic pressure after treatment in the two groups was significantly reduced, but the data in the study group was significantly lower than that in the control group. The above differences be-tween the two groups had statistical significance ( P<0. 05 ) . The blood pressure before and after treatment had no statistical difference between the two groups ( P>0. 05 ) . Conclusion The iloprost and NO inhalation can effectively reduce the airway pressure and pul-monary arterial systolic pressure, improve the oxygenation level. The rational nursing method can further increase the efficacy.
