CAJ | 학술논문

目的：比较应用桂枝茯苓丸分别联合3种治疗方式治疗子宫肌瘤的临床疗效。方法将57例子宫肌瘤患者随机均分为3组，采用桂枝茯苓丸分别联合腹腔镜下子宫肌瘤剔除术治疗（A组）、子宫动脉栓塞术治疗（B组）和高强度聚焦超声治疗（C组）。对比3组患者的临床疗效。结果3组患者手术时间、术后下床活动时间及住院天数比较，差异有统计学意义（ F=6.1683，P=0.0007；F=5.6144，P=0.0031；F=5.5671，P=0.0039），B组及C组均明显优于A组（ P﹤0.05），而B组及C组间比较差异无统计学意义( P﹥0.05)。C组患者术中未见出血，B组患者术中出血量明显低于A组（ P﹤0.05）。A组治疗总有效率为100.00%，B组为94.74%，C组为63.16%，B组明显优于C组，而A组及B组间比较，差异不明显。结论桂枝茯苓丸联合子宫动脉栓塞术较联合其他两种方式可有效提高治疗子宫肌瘤的疗效，值得临床推广。
목적：비교응용계지복령환분별연합3충치료방식치료자궁기류적림상료효。방법장57례자궁기류환자수궤균분위3조，채용계지복령환분별연합복강경하자궁기류척제술치료（A조）、자궁동맥전새술치료（B조）화고강도취초초성치료（C조）。대비3조환자적림상료효。결과3조환자수술시간、술후하상활동시간급주원천수비교，차이유통계학의의（ F=6.1683，P=0.0007；F=5.6144，P=0.0031；F=5.5671，P=0.0039），B조급C조균명현우우A조（ P﹤0.05），이B조급C조간비교차이무통계학의의( P﹥0.05)。C조환자술중미견출혈，B조환자술중출혈량명현저우A조（ P﹤0.05）。A조치료총유효솔위100.00%，B조위94.74%，C조위63.16%，B조명현우우C조，이A조급B조간비교，차이불명현。결론계지복령환연합자궁동맥전새술교연합기타량충방식가유효제고치료자궁기류적료효，치득림상추엄。
Objective To compare the clinical effect of Guizhifuling pills combined with 3 kinds of different therapeutic modes in treat-ing uterine fibroids. Methods 57 patients with uterine fibroids were randomly divided into 3 groups:the Guizhifuling Pills combined with laparoscopic myomectomy group(group A),the Guizhifuling Pills combined with uterine artery embolization group(group B)and the Guizhifuling Pills combined with high intensity focused ultrasound therapy(group C),19 cases in each group. The clinical therapeutic ef-fects were compared among the 3 groups. Results The operative time,postoperative ambulation activity time and hospitalization days had statistically significant differences among the 3 groups( F=6. 168 3,P=0. 000 7;F=5. 614 4,P=0. 003 1;F=5. 567 1,P=0. 003 9),the group B and C were significantly better than the group A( P ﹤ 0. 05),but the difference between group B and C had no sta-tistical significance ( P ﹥ 0. 05 ) . The patients in the group C had no intraoperative bleeding and the bleeding amount in the group B was significantly lower than that in the group A( P ﹤ 0. 05). The total therapeutic effective rate was 100. 00% in the group A, 94. 74% in the group B and 63. 16% in the group C,the group B was obviously superior to the group C,but there was no significant difference between the group A and group B. Conclusion Guizhifuling Pills combined with uterine artery embolization can effectively increase the efficacy in treating uterine fibroids than the other two Rind therapeutlic mades,which is worthy of clinical promotion.