CAJ | 학술논문

目的：分析并研究35例急性白血病形态学分型与免疫学分型结果，从而确定两者之间是否存在相关性。方法选取我院自2012年11月～2014年2月收治的初步诊断为急性白血病患者35例，将其作为临床研究对象，首先对35例出诊患者进行形态学分型，与此同时进行免疫学分型；随后对两组分型的诊断结果进行比较和分析，找到二者之间的相关性。结果通过形态学分型发现35例急性白血病中有25例AML，10例ALL。CD13，CD33，HLA-DR，MPO，CD19在AML中高表达，P＞0.05，差异无统计学意义有可比性，提示两分型具有相关性；CD19，CD68，HLA-DR在ALL中高表达，P＞0.05，差异无统计学意义有可比性，提示两分型具有相关性。结论实验结果表明两组分型具有较高的吻合度，在临床应用时应该相互结合和补充，避免误诊，有效的提高诊断结果的正确性，因此两种分型相结合的方法值得我们在临床上进行继续探讨和广泛应用。
목적：분석병연구35례급성백혈병형태학분형여면역학분형결과，종이학정량자지간시부존재상관성。방법선취아원자2012년11월～2014년2월수치적초보진단위급성백혈병환자35례，장기작위림상연구대상，수선대35례출진환자진행형태학분형，여차동시진행면역학분형；수후대량조분형적진단결과진행비교화분석，조도이자지간적상관성。결과통과형태학분형발현35례급성백혈병중유25례AML，10례ALL。CD13，CD33，HLA-DR，MPO，CD19재AML중고표체，P＞0.05，차이무통계학의의유가비성，제시량분형구유상관성；CD19，CD68，HLA-DR재ALL중고표체，P＞0.05，차이무통계학의의유가비성，제시량분형구유상관성。결론실험결과표명량조분형구유교고적문합도，재림상응용시응해상호결합화보충，피면오진，유효적제고진단결과적정학성，인차량충분형상결합적방법치득아문재림상상진행계속탐토화엄범응용。
Objective to analysis and study of 35 cases of acute leukemia type form for credit and immune credits as a result, to determine if there is a correlation between the two.Methods our hospital from November 2012 to February 2012 were preliminary diagnosis of acute leukemia patients and 35 cases as a clinical research object, ifrst of all type 35 patients with visits to credit form, at the same time with immune credits; Then the diagnostic results of two component type comparison and analysis, to ifnd the correlation between them.Results through credit form type found in 35 cases of acute leukemia with 25 cases of AML, 10 cases of ALL. CD13, CD33, HLA - DR, MPO, CD19 in AML high expression,P > 0.05, there was no statistically signiifcant difference, prompt type two correlation;CD19, CD68, HLA - DR expressed in ALL high,P > 0.05, there was no statistically signiifcant difference, prompt type two points.Conclusion the experimental results show that the two component model has high inosculation, should combine and complement each other in clinical application, avoid misdiagnosis, effectively improve the accuracy of the diagnosis, so the combination of two kinds of classiifcation method is worth us to continue to explore and widely used in clinical.