广州医科大学学报
廣州醫科大學學報
엄주의과대학학보
Academic Journal of Guangzhou Medical College
2014年
4期
78-80
,共3页
帕金森病%痰热动风型%自拟化痰熄风汤%临床疗效
帕金森病%痰熱動風型%自擬化痰熄風湯%臨床療效
파금삼병%담열동풍형%자의화담식풍탕%림상료효
Parkinson’ s disease%phlegm-heat dynamic wind type%eliminating phlegm and calming wind soup%clinical effect
目的：观察自拟化痰熄风汤治疗痰热动风型帕金森病的临床疗效。方法：根据随机数字表将2012年3月到2012年10月收治的符合研究标准的48例痰热动风型帕金森病患者作为研究对象，其中对照组(左旋多巴＋普拉克索)24例；治疗组(在对照组治疗基础上加用自拟化痰熄风汤)24例。采用统一帕金森病评定量表( UP-DRS)进行临床疗效评定；采用Webster氏l0项计分法判定中医证候疗效。结果：24例治疗组患者中治愈7例、显效7例、好转7例、无效3例，有效率88％；24例对照组患者中治愈6例、显效7例、好转6例、无效5例，有效率79％。治疗组有效率高于对照组( P<0.05)。两组治疗后Webster氏评分均较治疗前明显改善(P<0.05)，治疗组各中医证候进步率均优于对照组(P<0.05)。结论：在单纯西药治疗基础上，同时加用自拟化痰熄风汤治疗痰热动风型帕金森病患者，效果更明显，且无明显不良反应，提高患者生存质量。
目的：觀察自擬化痰熄風湯治療痰熱動風型帕金森病的臨床療效。方法：根據隨機數字錶將2012年3月到2012年10月收治的符閤研究標準的48例痰熱動風型帕金森病患者作為研究對象，其中對照組(左鏇多巴＋普拉剋索)24例；治療組(在對照組治療基礎上加用自擬化痰熄風湯)24例。採用統一帕金森病評定量錶( UP-DRS)進行臨床療效評定；採用Webster氏l0項計分法判定中醫證候療效。結果：24例治療組患者中治愈7例、顯效7例、好轉7例、無效3例，有效率88％；24例對照組患者中治愈6例、顯效7例、好轉6例、無效5例，有效率79％。治療組有效率高于對照組( P<0.05)。兩組治療後Webster氏評分均較治療前明顯改善(P<0.05)，治療組各中醫證候進步率均優于對照組(P<0.05)。結論：在單純西藥治療基礎上，同時加用自擬化痰熄風湯治療痰熱動風型帕金森病患者，效果更明顯，且無明顯不良反應，提高患者生存質量。
목적：관찰자의화담식풍탕치료담열동풍형파금삼병적림상료효。방법：근거수궤수자표장2012년3월도2012년10월수치적부합연구표준적48례담열동풍형파금삼병환자작위연구대상，기중대조조(좌선다파＋보랍극색)24례；치료조(재대조조치료기출상가용자의화담식풍탕)24례。채용통일파금삼병평정량표( UP-DRS)진행림상료효평정；채용Webster씨l0항계분법판정중의증후료효。결과：24례치료조환자중치유7례、현효7례、호전7례、무효3례，유효솔88％；24례대조조환자중치유6례、현효7례、호전6례、무효5례，유효솔79％。치료조유효솔고우대조조( P<0.05)。량조치료후Webster씨평분균교치료전명현개선(P<0.05)，치료조각중의증후진보솔균우우대조조(P<0.05)。결론：재단순서약치료기출상，동시가용자의화담식풍탕치료담열동풍형파금삼병환자，효과경명현，차무명현불량반응，제고환자생존질량。
Objective:To investigate the clinical effects of eliminating phlegm and calming wind soup on the treatment of phlegm-heat dynamic wind type of Parkinson’ s disease. Methods: 48 patients with phlegm-heat dynamic wind type of Parkinson’ s disease admitted in our hospital from March 2012 to October 2012 were selected and were randomly divided into two groups. There were 24 cases in the control group ( levodopa+pramipexole) , and 24 cases in the treatment group ( eliminating phlegm and calming wind soup was added on the basis of control group). The clinical effects were evaluated by unified Parkinson’s disease rating scale (UP-DRS);TCM syndrome was evaluated by Webster ’ s 10 items scoring method. Results: In 24 cases of the treatment group, there were 7 cases of being cured, 7 cases with efficacy, 7 cases with improved condition, 3 cases without efficacy, and the efficacy rate was 88%. In 24 cases of the control group, there were 6 cases of being cured, 7 cases with efficacy, 6 cases with improved condition, 5 cases without efficacy, and the efficacy rate was 79%. Then, the efficacy rate of the treatment group was higher than that of the control group ( P<0.05) . The Webster scores of both groups were significantly improved after treatment (P<0.05). The progress rate of TCM syndrome in the treatment group was better than that of the control group (P<0.05). Conclusions: The combination of eliminating phlegm and calming wind soup with western drugs has more obvious clinical effects, without significant adverse reaction to improve the quality of life of patients.
