CAJ | 학술논문

目的：探讨髓外浆细胞瘤的临床特点诊疗手段。方法：对1995年1月至2013年12月在本科室收治的18例髓外浆细胞瘤进行回顾性分析,其中单纯放射治疗2例(11.7％),综合治疗15例(83.3％),单纯手术1例(5.6％)。结果：中位随访71个月(5~263个月),2例(11.7％)局部复发,3例(16.7％)转化为多发性骨髓瘤,单纯手术或放射治疗5年生存率为0,综合治疗的3、5、10年生存率分别为83.3％(15/18)、77.8％(7/9)、71.4％、(5/7)。结论：综合治疗髓外浆细胞瘤可获得良好的局部控制率和长期生存率,部分髓外浆细胞瘤可向多发性骨髓瘤转化,故需密切观察。
목적：탐토수외장세포류적림상특점진료수단。방법：대1995년1월지2013년12월재본과실수치적18례수외장세포류진행회고성분석,기중단순방사치료2례(11.7％),종합치료15례(83.3％),단순수술1례(5.6％)。결과：중위수방71개월(5~263개월),2례(11.7％)국부복발,3례(16.7％)전화위다발성골수류,단순수술혹방사치료5년생존솔위0,종합치료적3、5、10년생존솔분별위83.3％(15/18)、77.8％(7/9)、71.4％、(5/7)。결론：종합치료수외장세포류가획득량호적국부공제솔화장기생존솔,부분수외장세포류가향다발성골수류전화,고수밀절관찰。
Objective:To investigate the clinical feature and treatment of extramedullary plasmacytoma ( EMP ) . Methods:18 patients with extramedullary plasmacytoma admitted in our hospital from January 1995 to December 2013 were evaluated retrospectively, including 2 cases treated by radiotherapy alone ( 11. 7%) , 15 cases treated by comprehensive treatment ( 83. 3%) , and 1 case by surgery alone ( 5. 6%) . Results: During median follow-up of 71months (5-263moths), 2 (11.7%) developed local recurrences and 3 (16.7%) were converted to multiple mydoma. The survival rate of 5-years surgery alone or radiotherapy was 0. The overall 3, 5, and 10-years survival rates were 83.3% (15/18), 77.8% (7/9) and 71.4% (5/7) respectively. Conclusions:Comprehensive treatment on extramednllary plasmacytoma has good local control rate and long-term survival rate. Part of extramednllary plasmacytoma may convert to multiple myeloma and need close follow-up.