CAJ | 학술논문

目的：初步研究鼻咽癌放疗对患者血压的影响及其机制。方法：随机抽取2011年12月至2014年3月收治本院的符合条件的60例鼻咽癌放治后患者及60例其他部位恶性肿瘤放疗后患者作为研究对象。统计分析患者放疗前及放疗1个月后的血压、心率等指标。结果：鼻咽癌放疗后组收缩压较放疗前组明显下降(P<0.05)。其他肿瘤放疗前后组收缩压比较，差异无统计学意义(P>0.05)。鼻咽癌组中血压下降率较其他部分肿瘤组明显偏高( P<0.05)，颈部淋巴结肿大组血压下降与无颈部淋巴结肿大组比较，差异无统计学意义( P>0.05)。鼻咽癌组血压下降组放疗前后平均心率比较，差异无统计学意义(P>0.05)。其他肿瘤组血压下降组放疗前后平均心率比较，差异有统计学意义(P<0.05)。结论：血压下降情况在鼻咽癌放疗患者中较其他肿瘤患者放疗后常见，颈动脉窦受压可能是其一个重要原因。
목적：초보연구비인암방료대환자혈압적영향급기궤제。방법：수궤추취2011년12월지2014년3월수치본원적부합조건적60례비인암방치후환자급60례기타부위악성종류방료후환자작위연구대상。통계분석환자방료전급방료1개월후적혈압、심솔등지표。결과：비인암방료후조수축압교방료전조명현하강(P<0.05)。기타종류방료전후조수축압비교，차이무통계학의의(P>0.05)。비인암조중혈압하강솔교기타부분종류조명현편고( P<0.05)，경부림파결종대조혈압하강여무경부림파결종대조비교，차이무통계학의의( P>0.05)。비인암조혈압하강조방료전후평균심솔비교，차이무통계학의의(P>0.05)。기타종류조혈압하강조방료전후평균심솔비교，차이유통계학의의(P<0.05)。결론：혈압하강정황재비인암방료환자중교기타종류환자방료후상견，경동맥두수압가능시기일개중요원인。
Objective:To preliminarily study the impact and mechanism of radiotherapy on blood pressure of patients with nasopharyngeal carcinoma ( NPC). Methods: 60 patients with NPC and 60 patients with other tumors matched the conditions were chosen randomly from December 2011 to March 2014 at our department. The blood pressure and heart rate of each patient were statically analyzed before and 1 month later of the radiotherapy. Results:The average systolic blood pressure of the patients with NPC was significantly decreased after radiotherapy ( P<0. 05 ) . There was no statistical significance of the systolic blood pressure of other tumors between before and after radiotherapy (P>0.05). The rate of patients whose average systolic blood pressure significantly declined in NPC group was significant higher than other tumors groups (P<0.05). The rates of patients whose average systolic blood pressure significantly declined after radotherapy were not significantly different between the swollen lymgh node group and the non-swollen lymgh node group (P>0.05). The average heart rate of patients with NPC was not changed significantly after radiotherapy (P>0.05), while the average heart rate of the patients with other tumors significantly increased after radiotharepy (P<0.05).Conclusion:Blood pressure decrease is more common in the patients with NPC after radiotheray than other tumors, the compression of sinus caroticus may be one of the important factors.